产品名称
抗髓磷脂碱性蛋白抗体, serum, Chemicon®
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... MBP(4155)
rat ... Mbp(24547)
Immunogen
对应豚鼠蛋白69-86位氨基酸的合成肽。免疫原对应于“降解"的髓磷脂碱性蛋白: YGSLPQKSQRSQDENPVV
Application
免疫组化:1:2,000。免疫染色脱髓鞘区域异常出现的少突胶质细胞过程和细胞体的髓鞘碱性蛋白。当在受损的脊髓和受损的坐骨神经中进行测试时,该抗体仅识别髓鞘变性区域。它还会染色多系统萎缩大脑中的离散白质。
最佳工作稀释度必须由最终用户确定。
最佳工作稀释度必须由最终用户确定。
抗髓鞘碱性蛋白抗体是用于IH的抗髓鞘碱性蛋白的抗体。
研究子类别
神经元& 胶质标记
神经退行性疾病
神经元& 胶质标记
神经退行性疾病
研究类别
神经科学
神经科学
Biochem/physiol Actions
识别脱髓鞘神经组织中的髓鞘碱性蛋白。病变大鼠脊髓的免疫组化分析显示该抗血清的高水平特异性。
Physical form
兔血清。 冻干,没有防腐剂。用50 μL无菌蒸馏水复溶。离心以除去所有残留物。
未纯化
Preparation Note
自收到之日起,在 -20-70° 以未稀释的等分试样可保存 12 个月。应避免反复冻/融循环。可以添加甘油(1:1)以获得额外的稳定性。
Analysis Note
对照
脑组织
脑组织
Other Notes
浓度:请参考批次特异性浓缩物的分析证书。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Brian D Clark et al.
Journal of neurotrauma, 20(7), 681-695 (2003-08-12)
Anatomical and physiological changes were evaluated in the median nerves of rats trained to perform repetitive reaching. Motor degradation was evident after 4 weeks. ED1-immunoreactive macrophages were seen in the transcarpal region of the median nerve of both forelimbs by
Role of myelin auto-antigens in pain: a female connection.
Veronica I Shubayev et al.
Neural regeneration research, 11(6), 890-891 (2016-08-03)
Andriy O Glushakov et al.
International journal of molecular sciences, 19(10) (2018-10-17)
Traumatic brain injury (TBI) is associated with long-term disabilities and devastating chronic neurological complications including problems with cognition, motor function, sensory processing, as well as behavioral deficits and mental health problems such as anxiety, depression, personality change and social unsuitability.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AB5864 | 04053252409134 |