species reactivity
human
Quality Level
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 63-118%, intra-assay cv: <10, sensitivity: 0.01-0.71 ng/mL
(MinDC+2SD), standard curve range: 0.01-5 ng/mL
(IP-10), standard curve range: 0.012-12.5 ng/mL
(EGF), standard curve range: 0.02-20 ng/mL
(PTH), standard curve range: 0.15-150 ng/mL
(FABP1), standard curve range: 0.17-1,200 ng/mL
(Osteopontin (OPN)), standard curve range: 0.20-200 ng/mL
(KIM-1), standard curve range: 0.68-700 ng/mL
(Renin)
technique(s)
multiplexing: suitable
input
serum
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
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General description
Application
Analytes included: α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN)
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Features and Benefits
- Measures 7 key biomarkers of kidney injury in human urine samples
- Includes α-1-Microglobulin, Albumin, Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, and Osteopontin (OPN)
- Magnetic bead-based format for enhanced precision and simplified washing
- Utilizes Luminex® xMAP® technology for multiplexing and high-throughput analysis
- Validated for human urine with recommended sample dilution of 1:100
- Assay sensitivity ranges from 0.015 to 5.359 ng/mL depending on the analyte
- Standard curve ranges from 0.01 to 5,000 ng/mL across analytes
- Intra-assay CV < 10%, inter-assay CV < 20%
- Enables early and specific detection of kidney injury before traditional markers like BUN and serum creatinine
- Provides insight into organ-specific damage and mechanisms of nephrotoxicity
- Conserves sample volume by analyzing multiple biomarkers in a single run
- Supports drug safety and toxicity research with high analytical performance
- Reduces assay variability and improves reproducibility across studies
- Compatible with both manual and automated workflows for flexible lab integration
Legal Information
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
相关内容
Multiplex toxicity assays enable researchers to simultaneously measure multiple toxicity biomarkers of various organs to gain a better understanding of toxicity. Explore how MILLIPLEX® multiplex toxicity assays are advancing research on liver injury, kidney toxicity, genotoxicity, and more.
Novel kidney toxicity biomarkers expand options for acute nephrotoxicity detection. Multiplex assays measure multiple renal damage biomarkers in small sample volumes, minimizing time and costs. See how MILLIPLEX® multiplex kidney toxicity assays detected vancomycin-induced subacute nephrotoxicity in rat models.
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