MAB2258
抗突触融合蛋白3-抗体，克隆1-146
clone 1-146, from mouse
别名:
syntaxin 3, syntaxin 3A
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
1-146, monoclonal
Application:
IHC, IP, WB
Citations:
11
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
1-146, monoclonal
species reactivity
human, rat
species reactivity (predicted by homology)
mouse
technique(s)
immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... STX3(6809)
rat ... Stx3(81802)
General description
大约33 kDa
突触融合蛋白-3，也称为Stx3，是SNARE家族的成员，SNARE家族是参与膜融合的复合物。 突触融合蛋白-3在上皮细胞中表达，并在MDCK和Caco-2细胞中顶端发现（1）。
Immunogen
GST标记的重组蛋白，对应于大鼠突触融合蛋白-3中包含的残基。
Application
使用经验证可用于WB、IP、IH的抗突触融合蛋白-3抗体（克隆1-146）检测突触融合蛋白-3。
研究子类别
突触&突触生物学
突触&突触生物学
研究类别
神经科学
神经科学
Biochem/physiol Actions
该抗体可识别突触融合蛋白-3。
Physical form
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ NaN3的缓冲液中的纯化的小鼠单克隆抗体。
形式：纯化
纯化的蛋白G
Preparation Note
自接收之日起，在2-8°C下冷藏保存1年。
Analysis Note
对照
大鼠脑组织裂解物
大鼠脑组织裂解物
通过蛋白质印迹在大鼠脑组织裂解物中进行了评估。
蛋白质印迹分析：： 该抗体0.5 µg/mL的稀释液在 15 µg 大鼠脑组织裂解物中检测到突触融合蛋白3。
蛋白质印迹分析：： 该抗体0.5 µg/mL的稀释液在 15 µg 大鼠脑组织裂解物中检测到突触融合蛋白3。
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Adrian J Giovannone et al.
The Journal of biological chemistry, 293(15), 5478-5491 (2018-02-25)
Syntaxins are a conserved family of SNARE proteins and contain C-terminal transmembrane anchors required for their membrane fusion activity. Here we show that Stx3 (syntaxin 3) unexpectedly also functions as a nuclear regulator of gene expression. We found that alternative
Daniëlle Rianne José Verboogen et al.
eLife, 6 (2017-05-20)
SNARE proteins play a crucial role in intracellular trafficking by catalyzing membrane fusion, but assigning SNAREs to specific intracellular transport routes is challenging with current techniques. We developed a novel Förster resonance energy transfer-fluorescence lifetime imaging microscopy (FRET-FLIM)-based technique allowing
Ying Hsu et al.
Molecular therapy. Nucleic acids, 31, 164-181 (2023-01-27)
Blindness in Bardet-Biedl syndrome (BBS) is caused by dysfunction and loss of photoreceptor cells in the retina. BBS10, mutations of which account for approximately 21% of all BBS cases, encodes a chaperonin protein indispensable for the assembly of the BBSome
Ritika Chatterjee et al.
Traffic (Copenhagen, Denmark), 24(7), 270-283 (2023-04-28)
Intracellular membrane fusion is mediated by membrane-bridging complexes of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). SNARE proteins are one of the key players in vesicular transport. Several reports shed light on intracellular bacteria modulating host SNARE machinery to establish
Hiroshi Gomi et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 65(11), 637-653 (2017-09-16)
The comparative structure and expression of salivary components and vesicular transport proteins in the canine major salivary glands were investigated. Histochemical analysis revealed that the morphology of the five major salivary glands-parotid, submandibular, polystomatic sublingual, monostomatic sublingual, and zygomatic glands-was
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