MAB3662
Anti-TIF1 beta Antibody
ascites fluid, Chemicon®
别名:
TIF1beta
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
monoclonal
Application:
ELISA, ICC, WB
Citations:
15
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
monoclonal
species reactivity
mouse, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunocytochemistry: suitable, western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TRIM28(10155)
Immunogen
Recombinant protein from mouse TIF1b.
Application
Anti-TIF1 beta Antibody is a Mouse Monoclonal Antibody for detection of Transcriptional Intermediary Factor 1 also known as TIF1 beta & has been validated in ELISA, WB, ICC.
Western blot: 1:500-1:5,000
Immunocytochemistry: 1:500-1:5,000
ELISA: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Immunocytochemistry: 1:500-1:5,000
ELISA: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes transcriptional intermediary factor 1beta (TIF1beta). The epitope is localized between amino acids 123-834 of mouse TIF1beta. No cross reactivity with TIF1alpha.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Nozomi Takahashi et al.
Genes & development, 33(1-2), 49-54 (2019-01-04)
Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation, causing parental origin-specific monoallelic gene expression. Zinc finger protein 57 (ZFP57) is critical for maintenance of this epigenetic memory during post-fertilization reprogramming, yet incomplete penetrance of ZFP57 mutations in
Andrea Coluccio et al.
Epigenetics & chromatin, 11(1), 7-7 (2018-02-28)
The KZFP/KAP1 (KRAB zinc finger proteins/KRAB-associated protein 1) system plays a central role in repressing transposable elements (TEs) and maintaining parent-of-origin DNA methylation at imprinting control regions (ICRs) during the wave of genome-wide reprogramming that precedes implantation. In naïve murine
Christopher Hc Tie et al.
EMBO reports, 19(10) (2018-08-01)
Endogenous retroviruses (ERVs) have accumulated in vertebrate genomes and contribute to the complexity of gene regulation. KAP1 represses ERVs during development by its recruitment to their repetitive sequences through KRAB zinc-finger proteins (KZNFs), but little is known about the regulation
Mathieu Boulard et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(25), 14292-14298 (2020-06-12)
The mechanisms by which methylated mammalian promoters are transcriptionally silenced even in the presence of all of the factors required for their expression have long been a major unresolved issue in the field of epigenetics. Repression requires the assembly of
Helen M Rowe et al.
Development (Cambridge, England), 140(3), 519-529 (2013-01-08)
Endogenous retroviruses (ERVs) undergo de novo DNA methylation during the first few days of mammalian embryogenesis, although the factors that control the targeting of this process are largely unknown. We asked whether KAP1 (KRAB-associated protein 1) is involved in this
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