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Merck
CN

OP134

Anti-IKKβ Mouse mAb (10AG2)

liquid, clone 10AG2, Calbiochem®

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UNSPSC Code:
12352203
Clone:
10AG2, monoclonal
Species reactivity:
human
Application:
Citations:
2
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biological source

mouse

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

10AG2, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

do not freeze

isotype

IgG1

shipped in

wet ice

Quality Level

Gene Information

human ... IKBKB(3551)

target post-translational modification

unmodified

General description

Immunoaffinity purified mouse monoclonal antibody. Recognizes the ~87 kDa IKKβ protein.
Recognizes the ~87 kDa IKKβ protein in Daudi cells.
This Anti-IKKβ Mouse mAb (10AG2) is validated for use in Immunoblotting for the detection of IKKβ.

Immunogen

Human
a recombinant protein consisting of full-length human IKKβ fused to a His•Tag sequence

Application


Immunoblotting (1-4 g/ml, chemiluminescence)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, 0.2% gelatin, pH 7.4.

Analysis Note

Positive Control
Daudi cells

Other Notes

Antibody should be titrated for optimal results in individual systems.
Delhase, M., et al. 1999. Science284, 309.
Li. Q., et al. 1999. Science284, 321.
Didonato, et al. 1997. Nature388, 548.
Lee, F.S., et al. 1997. Cell88, 213.
Malinin, N.L., et al. 1997. Nature385, 540.
Mercurio, F., et al. 1997. Science278, 860.
Regnier, C.H., et al. 1997. Cell90, 373.
Verma, I. And Stevenson, J.K. 1997. Proc. Nat. Acad. Sci. USA94, 11758.
Verma, I.M., et al. 1995. Genes. Dev.9, 2723.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Jonathan M Starkey et al.
Diabetes, 55(5), 1252-1259 (2006-04-29)
Evidence of diabetes-induced nuclear factor-kappaB (NF-kappaB) activation has been provided with DNA binding assays or nuclear localization with immunohistochemistry, but few studies have explored mechanisms involved. We examined effects of diabetes on proteins comprising NF-kappaB canonical and noncanonical activation pathways
Tamara P Martin et al.
Cellular signalling, 51, 166-175 (2018-07-31)
Calcium/calmodulin dependent protein kinase IIδ (CaMKIIδ) acts as a molecular switch regulating cardiovascular Ca2+ handling and contractility in health and disease. Activation of CaMKIIδ is also known to regulate cardiovascular inflammation and is reported to be required for pro-inflammatory NF-κB

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