AB2256
抗-GABA B受体R1抗体
serum, from guinea pig
别名:
GABA-B receptor, GABA-B receptor 1, GABAB, subunit 1c, gamma-aminobutyric acid (GABA) B receptor 1, gamma-aminobutyric acid B receptor 1, seven transmembrane helix receptor
产品名称
抗-GABA B受体R1抗体, serum, from guinea pig
biological source
guinea pig
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, human, rat
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Gabbr1(54393)
Biochem/physiol Actions
与其他物种的反应性尚未确定。
目录 # AB2256可识别GABA B受体R1（GABA B R1）
Analysis Note
对照
大鼠脑裂解液
大鼠脑裂解液
蛋白质印迹：先前批次的1:1,000稀释液在10µg大鼠脑裂解液中检测到GABA B R1。
Application
使用经验证可用于WB，IH的抗GABA B受体R1抗体检测GABA B受体R1。
免疫组化：在自由漂浮的小鼠脑组织中的工作稀释度为1:3,000。
研究子类别
神经递质& 受体
神经递质& 受体
研究类别
神经科学
神经科学
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
γ-氨基丁酸（GABA）是哺乳动物中枢神经紧张的系统中主要的抑制性神经递质。GABA通过离子型[GABA（A/C）]受体发挥其作用，以产生快速的突触抑制，而代谢型[GABA（B）]受体则产生缓慢，延长的抑制信号。GABA（B）受体由两个相关的7跨膜受体GABA（B）受体1和GABA（B）受体2的异二聚体组成。GABA（B）受体1基因被定位到靠近HLA-F基因的HLA I类区域内的染色体6p21.3。多发性硬化、癫痫和精神分裂症的易感基因座也已定位于该区域。该基因的可变剪接产生4个转录物变体。
~100-105 kDa
Immunogen
表位：C端
相互作用w/ ATF4
相互作用w/ ATF4
重组肽（aa 972-991：PSEPPDRLSCDGSRVHLLYK）
Physical form
含0.05%NaN3的GST耗尽血清。
Preparation Note
自收到之日起在-20ºC可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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