AB2261
抗Tbr1抗体
from chicken, purified by affinity chromatography
别名:
T-box, brain, 1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
human, mouse, rat
Citations:
39
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗Tbr1抗体, from chicken, purified by affinity chromatography
biological source
chicken
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse, rat
species reactivity (predicted by homology)
opossum (based on 100% sequence homology), horse (based on 100% sequence homology), canine (based on 100% sequence homology), bovine (based on 100% sequence homology), pig (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Tbr1(21375)
Application
抗Tbr1抗体是用于WB，IH的针对Tbr1的抗体。
研究子类别
发育神经科学
发育神经科学
研究类别
神经科学
神经科学
免疫组化分析： 一个先前批次的1：100稀释液在小鼠额叶皮质组织中检测到Tbr1。
Biochem/physiol Actions
该抗体可识别Tbr1。
Analysis Note
对照
人胎脑组织裂解液
人胎脑组织裂解液
通过蛋白质印迹在人胎脑组织裂解液中进行了评估。
蛋白质印迹分析：0.025 µg/mL的该抗体在10 µg人胎脑组织裂解液中检测到Tbr1。
蛋白质印迹分析：0.025 µg/mL的该抗体在10 µg人胎脑组织裂解液中检测到Tbr1。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Tbr1基因是一个保守的基因家族的成员，该家族共享一个共同的DNA结合结构域T-box。T-box基因编码参与发育过程调控的转录因子。Tbr1是一种已知在有丝分裂后神经元中表达的推定转录因子，已在谷氨酸能的早产皮质神经元中高度表达。类似的蛋白已在小鼠中被破坏，并显示出对早期皮质发育至关重要，并导致嗅球和嗅觉皮质中投射神经元的丢失。发现Tbr1衍生的蛋白的C末端区域对于与钙/钙调蛋白依赖性丝氨酸蛋白激酶的鸟苷酸激酶结构域关联性是必要和充分的。
观察值为~ 68 kDa；然而，UniProtKB/Swiss-Prot条目Q64336（TBR1_MOUSE）列出了73.941 kDa的质量
Immunogen
对应于小鼠Tbr1的KLH偶联线性肽。
表位：内部
Other Notes
Physical form
亲和纯化
纯化的鸡多克隆抗体溶于含0.1 M Tris-甘氨酸（pH 7.4，150 mM NaCl）和0.05％叠氮化钠的缓冲液中。
Preparation Note
自发运之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Leslie E W LaConte et al.
Human genetics, 137(3), 231-246 (2018-02-11)
Deletion and truncation mutations in the X-linked gene CASK are associated with severe intellectual disability (ID), microcephaly and pontine and cerebellar hypoplasia in girls (MICPCH). The molecular origin of CASK-linked MICPCH is presumed to be due to disruption of the
Livio Oboti et al.
eNeuro, 5(3) (2018-06-19)
Interconnections between the olfactory bulb and the amygdala are a major pathway for triggering strong behavioral responses to a variety of odorants. However, while this broad mapping has been established, the patterns of amygdala feedback connectivity and the influence on
Shama Parween et al.
Frontiers in cellular neuroscience, 11, 415-415 (2018-01-10)
The nutrient responsive O-GlcNAcylation is a dynamic post-translational protein modification found on several nucleocytoplasmic proteins. Previous studies have suggested that hyperglycemia induces the levels of total O-GlcNAcylation inside the cells. Hyperglycemia mediated increase in protein O-GlcNAcylation has been shown to
Evelyn McClendon et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(49), 11912-11929 (2017-11-02)
Preterm infants are at risk for a broad spectrum of neurobehavioral disabilities associated with diffuse disturbances in cortical growth and development. During brain development, subplate neurons (SPNs) are a largely transient population that serves a critical role to establish functional
Shinsuke Shibata et al.
Frontiers in neural circuits, 13, 29-29 (2019-05-28)
Recent improvements in correlative light and electron microscopy (CLEM) technology have led to dramatic improvements in the ability to observe tissues and cells. Fluorescence labeling has been used to visualize the localization of molecules of interest through immunostaining or genetic
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