biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PRDM14(63978)
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General description
PR结构域蛋白(PRDM)与多种人类癌症有关。研究发现,PRDM14在乳腺癌细胞中表达上调。乳腺癌细胞中PRDM14的表达实际上增加了细胞增殖、降低了化疗药物的作用,而PRDM14的下调则作用相反。除乳腺癌外,最近还发现PRDM14与非小细胞肺癌的进展有关。PRDM14似乎在保持人类胚胎干细胞的自我更新和转录调控方面也发挥作用。
观测值〜62 kDa
Immunogen
GST标记的重组蛋白,对应于人PRDM14的N端。
Application
这种PRDM14抗体经验证可用于WB检测PRDM14。
Biochem/physiol Actions
该抗体可识别PRDM14的N端。
Analysis Note
已通过蛋白质印迹法在人肺组织裂解液中进行了评估。
蛋白质印迹分析:该抗体的1:1000稀释液在10 µg人肺组织裂解液中检测到PRDM14。
蛋白质印迹分析:该抗体的1:1000稀释液在10 µg人肺组织裂解液中检测到PRDM14。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
SOX17 is a critical specifier of human primordial germ cell fate.
Irie, N; Weinberger, L; Tang, WW; Kobayashi, T; Viukov, S; Manor, YS; Dietmann, S; Hanna et al.
Cell null
Yu Kang et al.
Cell reports, 25(9), 2563-2576 (2018-11-30)
Monkeys are an optimal model species for developing stem cell therapies. We previously reported generating chimeric cynomolgus monkey fetuses using dome-shaped embryonic stem cells (dESCs). However, conventional primed pluripotent stem cells (pPSCs) lack chimera competency. Here, by altering the media
Pengyi Yang et al.
Cell systems, 8(5), 427-445 (2019-05-13)
Pluripotency is highly dynamic and progresses through a continuum of pluripotent stem cell states. The two states that bookend the pluripotency continuum, naive and primed, are well characterized, but our understanding of the intermediate states and transitions between them remains
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