产品名称
抗-Sox10抗体, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Application
抗-Sox10抗体检测Sox10水平,已发布,经验证可用于WB。
研究子类别
发育神经科学
神经&胶质标志物
发育神经科学
神经&胶质标志物
研究类别
神经科学
神经科学
蛋白质印迹:0.1-0.5 μg/mL,对胎鼠脑组织裂解液使用ECL。该抗体与~60 kDa的蛋白反应。根据所使用的样品,还可能会出现一个 〜120 kDa 的额外的条带。
最佳工作稀释度必须由最终用户进行确定。
最佳工作稀释度必须由最终用户进行确定。
Biochem/physiol Actions
Sox10。 免疫原序列与Sox8和Sox9有70%的保守性,因此抗体可能会与这些蛋白产生交叉反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Sox 10是转录因子家族的成员,参与调节胚胎发育和确定细胞去向。编码蛋白在与其他蛋白形成蛋白复合物后可作为转录激活因子。该蛋白作为核细胞质穿梭蛋白,在神经嵴和周围神经系统发育中起重要作用。sox10在多能神经嵴干细胞中表达,其表达在其分化过程中下调。该基因的突变与瓦登堡-沙赫病和瓦登堡-赫氏病有关。
大约55 kDa
Immunogen
Sox10的合成肽。
Other Notes
替代:AB5774
Physical form
亲和纯化的免疫球蛋白。 液体。
Preparation Note
接收后,以未稀释的等分试样在+2-8°C下保存长达6个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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