Product Name
Anti-Tyrosine Hydroxylase Antibody, serum, Chemicon®
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
rat ... Th(25085)
免疫原
Synthetic peptide corresponding to amino acids 32-47 of rat Tyrosine Hydroxylase.
应用
Immunohistochemistry: 1:2,000-1:4,000.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neuronal & Glial Markers
Neurotransmitters & Receptors
Neuronal & Glial Markers
This Anti-Tyrosine Hydroxylase Antibody is validated for use in IH for the detection of Tyrosine Hydroxylase.
生化/生理作用
Tyrosine Hydroxylase. Immunohistochemical distribution throughout the brain shows that staining is restricted to those neurons known to contain the enzyme. The antibody has proven useful in staining catecholaminergic neurons. AB5986 stains these neurons intensely, including dendritic processes and fine nerve terminals.
外形
Rabbit serum. Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
制备说明
Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.
分析说明
Control
POSITIVE CONTROL: brain (sympathetic nerve terminals) and adrenal glands.
POSITIVE CONTROL: brain (sympathetic nerve terminals) and adrenal glands.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
S M Miller et al.
Neuroscience, 159(4), 1384-1396 (2009-05-05)
Dopamine receptor activity in the rodent medial preoptic area (mPOA) is crucial for the display of maternal behaviors, as well as numerous other physiological and behavioral functions. However, the origin of dopaminergic input to the mPOA has not been identified
Neurotransmitters in airway parasympathetic neurons altered by neurotrophin-3 and repeated allergen challenge.
Pan, J; Rhode, HK; Undem, BJ; Myers, AC
American Journal of Respiratory Cell and Molecular Biology null
Alice Drobny et al.
Translational neurodegeneration, 12(1), 31-31 (2023-06-14)
Lysosomal dysfunction has been implicated in a number of neurodegenerative diseases such as Parkinson's disease (PD). Various molecular, clinical and genetic studies have highlighted a central role of lysosomal pathways and proteins in the pathogenesis of PD. Within PD pathology
Jennie L Close et al.
Neuron, 93(5), 1035-1048 (2017-03-11)
GABAergic interneurons are essential for neural circuit function, and their loss or dysfunction is implicated in human neuropsychiatric disease. In vitro methods for interneuron generation hold promise for studying human cellular and functional properties and, ultimately, for therapeutic cell replacement. Here
Iva Stojkovska et al.
Neuron, 110(3), 436-451 (2021-11-19)
Neurodegenerative disorders are characterized by a collapse in proteostasis, as shown by the accumulation of insoluble protein aggregates in the brain. Proteostasis involves a balance of protein synthesis, folding, trafficking, and degradation, but how aggregates perturb these pathways is unknown.
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