biological source
rabbit
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
species reactivity
chicken
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, radioimmunoassay: suitable
suitability
not suitable for Western blot, not suitable for immunohistochemistry (Paraffin)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... COL1A1(1277)
General description
Rabbit polyclonal antibodies against Collagen Type I extracted and purified from chicken skin. Antibody shows less than 0.1% reactivity with chicken Collagen Types III, V and human, bovine, mouse, rat Collagen Type I and chicken Fibronectin.
Application
Detect Collagen Type I using this Anti-Collagen Type I Antibody validated for use in ELISA, RIA, IH.
Immunohistochemistry: 1:40 dilution for immunofluorescent staining of frozen chicken skin and liver tissues.
Radioimmunoassay
ELISA
Not recommended for paraffin embedded tissue sections or Western blots. Optimal working dilutions must be determined by end user.
Radioimmunoassay
ELISA
Not recommended for paraffin embedded tissue sections or Western blots. Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Biochem/physiol Actions
Chicken collagen type I 100%. Less than 0.4% reactivity to chicken collagen type III, mouse collagen type I, rat collagen type I, bovine collagen type I and human collagen type I.
Physical form
Format: Purified
IgG fraction. Liquid in 0.01 M phosphate, 0.09 M NaCL, pH 7.2, containing no preservatives.
Preparation Note
Maintain frozen at -20°C for up to 12 months. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: AB752
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Hong Tan et al.
Developmental biology, 374(2), 345-356 (2012-12-25)
Fibrous development of the extracellular matrix (ECM) of cardiac valves is necessary for proper heart function. Pathological remodeling of valve ECM is observed in both pediatric and adult cardiac disorders. It is well established that intracardiac hemodynamics play a significant
Lei Wang et al.
The Journal of biological chemistry, 289(2), 921-929 (2013-11-23)
Corneal stroma contains an extracellular matrix of orthogonal lamellae formed by parallel and equidistant fibrils with a homogeneous diameter of ~35 nm. This is indispensable for corneal transparency and mechanical functions. However, the mechanisms controlling corneal fibrillogenesis are incompletely understood
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