产品名称
抗髓磷脂碱性蛋白抗体, Chemicon®, from chicken
biological source
chicken
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MBP(4155)
mouse ... Mbp(17196)
Application
免疫组化：1:50-1：100，使用2%多聚甲醛固定的组织。
免疫细胞化学：1:50-1：100，使用2%多聚甲醛固定的细胞。
最佳工作稀释度必须由最终用户进行确定。
免疫细胞化学：1:50-1：100，使用2%多聚甲醛固定的细胞。
最佳工作稀释度必须由最终用户进行确定。
抗髓鞘碱性蛋白抗体可检测髓鞘碱性蛋白的水平&已发表&经验证可用于IC，IH。
研究子类别
神经 & 胶质标记物
神经化学 & 神经营养因子
神经 & 胶质标记物
神经化学 & 神经营养因子
研究类别
神经科学
神经科学
Biochem/physiol Actions
识别髓鞘碱性蛋白（MBP）。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
来自人/小鼠MBP的合成肽。
Other Notes
Physical form
亲和纯化的鸡IgY。 含有0.02%叠氮化钠的PBS pH值7.2中的液体。
Preparation Note
自收到之日起，在 2-8° 以未稀释的等分试样可保存 6 个月。建议您将抗体避光保存。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Caroline Guglielmetti et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(33), E6982-E6991 (2017-08-02)
Proinflammatory mononuclear phagocytes (MPs) play a crucial role in the progression of multiple sclerosis (MS) and other neurodegenerative diseases. Despite advances in neuroimaging, there are currently limited available methods enabling noninvasive detection of MPs in vivo. Interestingly, upon activation and
José Javier Miguel-Hidalgo et al.
Chronic stress (Thousand Oaks, Calif.), 2 (2019-02-19)
Astrocytes and oligodendrocytes are pathologically altered in dorsolateral prefrontal and orbitofrontal cortices in major depressive disorder. In rat models of stress (major depressive disorder risk factor) astrocyte gap junction protein connexin 43 (Cx43) is reduced in the prelimbic cortex. Astrocyte
C Guglielmetti et al.
NeuroImage, 125, 363-377 (2015-11-04)
Although MRI is the gold standard for the diagnosis and monitoring of multiple sclerosis (MS), current conventional MRI techniques often fail to detect cortical alterations and provide little information about gliosis, axonal damage and myelin status of lesioned areas. Diffusion
The 4.1B cytoskeletal protein regulates the domain organization and sheath thickness of myelinated axons.
Einheber, S; Meng, X; Rubin, M; Lam, I; Mohandas, N; An, X; Shrager, P; Kissil, J; Maurel et al.
Glia null
Debbie Le Blon et al.
Journal of neuroinflammation, 13(1), 288-288 (2016-11-11)
Promoting the neuroprotective and repair-inducing effector functions of microglia and macrophages, by means of M2 polarisation or alternative activation, is expected to become a new therapeutic approach for central nervous system (CNS) disorders in which detrimental pro-inflammatory microglia and/or macrophages
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