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Merck
CN

AB9612

Anti-Brain Derived Neurotrophic Factor Antibody

serum, Chemicon®

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
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Quality Level

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... BDNF(627)

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Immunogen

Synthetic peptide from mouse BDNF.

Application

Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neuroinflammation & Pain
This Anti-Brain Derived Neurotrophic Factor Antibody is validated for use in WB for the detection of Brain Derived Neurotrophic Factor.
Western blot: 1:500-1:2,000

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Brain Derived Neurotrophic Factor (BDNF). By Western blot the antibody reacts with recombinant BDNF protein and also detects the ~28 kDa proBDNF protein in rat brain extracts. The antibody shows no cross reactivity with NGF, NT3 or NT4/5 by Western blot.

Physical form

Rabbit serum. Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material.

Preparation Note

Maintain lyophilized material at -20 to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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A novel activator of CBP/p300 acetyltransferases promotes neurogenesis and extends memory duration in adult mice.
Chatterjee, S; Mizar, P; Cassel, R; Neidl, R; Selvi, BR; Mohankrishna, DV; Vedamurthy et al.
The Journal of Neuroscience null
Romain Neidl et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(15), 4351-4361 (2016-04-15)
Aging weakens memory functions. Exposing healthy rodents or pathological rodent models to environmental enrichment (EE) housing improves their cognitive functions by changing neuronal levels of excitation, cellular signaling, and plasticity, notably in the hippocampus. At the molecular level, brain derived-neurotrophic

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