生物来源
rabbit
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
rat, human, mouse
制造商/商品名称
Chemicon®
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... HSPA1A(3303)
mouse ... Hspa1A(193740)
rat ... Hspa1A(24472)
一般描述
70 kDa
The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell′s machinery for protein folding, and help to protect cells from stress
免疫原
Epitope: AA 122 - 400
Recombinant human HSP70
应用
Suggested dilutions:
Western Blot: 1:5000
Western Blot: 1:5000
Detect Heat Shock Protein 70 (HSP 70) using this Anti-Heat Shock Protein 70 (HSP 70) Antibody validated for use in WB.
Research Category
Metabolism
Metabolism
Research Sub Category
Enzymes & Biochemistry
Enzymes & Biochemistry
外形
Raw rabbit serum with 0.05% sodium azide.
制备说明
Maintain at -20°C for up to 12 months from date of receipt.
分析说明
Routinely evaluated by western blot.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Zhenkui Ren et al.
Molecular medicine reports, 22(1), 201-208 (2020-05-08)
Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disorder. Abnormal aggregation of the neurotoxic amyloid‑β (Aβ) peptide is an early event in AD. The activation of astrocytic α7 nicotinic acetylcholine receptor (α7 nAChR) can inhibit Aβ aggregation; thus, the
Chang-Sook Hong et al.
Journal of extracellular vesicles, 5, 29289-29289 (2016-03-29)
Isolation from human plasma of exosomes that retain functional and morphological integrity for probing their protein, lipid and nucleic acid content is a priority for the future use of exosomes as biomarkers. A method that meets these criteria and can
Thaís L S Araujo et al.
Cell stress & chaperones, 24(1), 273-282 (2019-01-16)
Heat shock protein-70 (HSP70) is crucial for proteostasis and displays cell-protective effects. Meanwhile, enhanced levels of cell-surface (cs) and secreted HSP70 paradoxically associate with pathologic cardiovascular conditions. However, mechanisms regulating csHSP70 pool are unknown. We hypothesized that total and csHSP70
Wenbo Zhou et al.
PloS one, 12(12), e0190160-e0190160 (2017-12-23)
Exercise has been recommended to improve motor function in Parkinson patients, but its value in altering progression of disease is unknown. In this study, we examined the neuroprotective effects of running wheel exercise in mice. In adult wild-type mice, one
Amanda M Gleixner et al.
Molecular neurobiology, 53(7), 4939-4960 (2015-09-17)
Astrocytes are one of the major cell types to combat cellular stress and protect neighboring neurons from injury. In order to fulfill this important role, astrocytes must sense and respond to toxic stimuli, perhaps including stimuli that are severely stressful
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