biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
primate (based on 100% sequence homology)
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... NOXA1(10811)
General description
NOXA1 (NADPH oxidase activator 1; Antigen NY-CO-31; NCF2-like protein; P67phox-like factor; p51-nox) is an activator of the NADPH oxidase NOX1. It contains multiple domains, including four TPR repeats which facilitate interaction with RAC1, and one SH3 domain that binds to NOXO1. NOXA1 interacts with NOXO1, RAC1, NOX1, and CYBA to form a multi-protein complex that produces reactive oxygen species for important cellular processes such as oxygen sensing, hormone biosynthesis, and signal transduction. NOXA1 is found in pancreas, spleen, liver, prostate, colon, and small intestine.
~51 kDa observed
Immunogen
KLH-conjugated linear peptide corresponding to human NOXA1.
Application
Detect NOXA1 using this Anti-NOXA1 Antibody validated for use in Western Blotting.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Biochem/physiol Actions
No homology to Rat or Mouse detected.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
Human colon tissue lysate
Human colon tissue lysate
Evaluated by Western Blot in Human Colon tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected NOXA1 in 10 µg of human colon tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected NOXA1 in 10 µg of human colon tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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