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Merck
CN

ABC427

Anti-ANT2 Antibody

from rabbit, purified by affinity chromatography

别名:

ADP/ATP translocase 2, ADP,ATP carrier protein 2, ADP,ATP carrier protein, fibroblast isoform, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5, ADP/ATP translocase 2, N-terminally processed

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
ICC, WB
Citations:
-
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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

avian (based on 100% sequence homology), fish (based on 100% sequence homology), nonhuman primates (based on 100% sequence homology), chicken (based on 100% sequence homology), rat (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SLC25A5(292)

General description

ANT2, also known as ADP/ATP translocase 2, ADP, ATP carrier protein 2, ADP, ATP carrier protein, fibroblast isoform, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5, and encoded by the gene symbol SLC25A5/ ANT2 is a member of the mitochondrial carrier (TC 2.A.29) family. ANT2 has been implied to catalyze the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex, ANT2 may play a role in chromosome segregation. ANT2 is a homodimer and a component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Recent studies have indicated that ANT2 interacts with HIV-1 Vpr. ANT2 is a multi-pass membrane protein and is located in the mitochondrion inner membrane.
~30 kDa observed

Immunogen

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of human ANT2.

Application

Anti-ANT2 is an antibody against ANT2 for use in WB, ICC.
Immunocytochemistry Analysis: A 1:1,000 dilution from a representative lot detected ANT2 in SK-BR3 cells.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in SK-BR3 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected ANT2 in 10 µg of SK-BR3 cell lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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