ABC512
Anti-ST6GAL1 Antibody
from rabbit, purified by affinity chromatography
别名:
Beta-galactoside alpha-2,6-sialyltransferase 1, Alpha 2,6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6Gal I, ST6GalI, Sialyltransferase 1
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
chimpanzee (based on 100% sequence homology), primate (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ST6GAL1(6480)
General description
ST6GAL1, also known as Beta-galactoside alpha-2/ 6-sialyltransferase 1, or Alpha 2/ 6-ST 1, and encoded by the gene symbol ST6GAL1/ SIAT1, is a member of the glycosyltransferase 29 family. ST6GAL1 has been implied to play an important role in the transfer of sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. The membrane-bound form of ST6GAL1 is located in trans-cisternae of Golgi apparatus. The soluble form of ST6GAL1 is derived from the membrane form by proteolytic processing. ST6GAL1 is located in the Golgi apparatus, Golgi stack membrane, and the Single-pass type II membrane protein.
~41 kDa observed. The calculated molecular weight is 47 kDa, however ST6GAL1 has been shown as a ~41 kDa band in western blots (Minyoung, L., et al. (2008). Mol. Cancer Research. 6:1316-1325).
Immunogen
Epitope: Lumenal domain
KLH-conjugated linear peptide corresponding to the Lumenal domain of human ST6GAL1.
Application
Anti-ST6GAL1 is an antibody against ST6GAL1 for use in WB, IH.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ST6GAL1 in human prostate and human liver cancer tissue.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in human skeletal muscle tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected ST6GAL1 in 10 µg of human skeletal muscle tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected ST6GAL1 in 10 µg of human skeletal muscle tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yun Tao et al.
Cytotechnology, 71(6), 1155-1165 (2019-11-11)
MiR-214-3p is concerned with the outcomes of various tumors, such as liver cancer, bladder cancer, etc. However, the role and target of miR-214-3p in triple negative breast cancer (TNBC) is not fully understood. This study took this as the entry
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