Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody

Histone-lysine N-methyltransferase SUV39H2 is also called Histone H3-K9 methyltransferase 2 (H3-K9-HMTase 2), Lysine N-methyltransferase 1B, and Suppressor of variegation 3-9 homolog 2 (Su(var)3-9 homolog 2). Histone-lysine N-methyltransferase SUV39H2 is a histone methyltransferase that specifically trimethylates ′Lys-9′ of histone H3 using monomethylated H3 ′Lys-9′ as substrate, which creates a specific tag for epigenetic transcriptional repression and directs DNA methylation at pericentric repeats. Histone-lysine N-methyltransferase SUV39H2 is involved in several processes, including cell cycle regulation, transcriptional repression, regulation of telomere length, and higher-order chromatin organization during spermatogenesis.

~51 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

KLH-conjugated linear peptide corresponding to human Histone-lys N-methyltransferase SUV39H2.

Detect SUV39H1 using this rabbit polyclonal antibody, Anti-Histone-lysine N-methyltransferase SUV39H2 Antibody validated for use in western blotting & IP.

Immunoprecipitation Analysis: 10 µg from a representative lot detected Histone-lys N-methyltransferase SUV39H2 in 500 µg of MDA-MB-435 cell lysate.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human testis tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected Histone-lys N-methyltransferase SUV39H2 in 10 µg of human testis tissue lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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