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Merck
CN

ABF211

Anti-Tirap Antibody

from rabbit, purified by affinity chromatography

别名:

Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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biological source

rabbit

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

species reactivity (predicted by homology)

mouse (immunogen homology)

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TIRAP(114609)

General description

Toll/interleukin-1 receptor domain-containing adapter protein (Tirap), also known as MyD88 adapter-like protein (Mal), contains one TIR domain that is involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection serving as an important link between the innate and adaptive immune responses.
~35 kDa observed

Immunogen

Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of mouse Tirap.

Application

Detect Toll/interleukin-1 receptor domain-containing adapter protein using this rabbit polyclonal antibody, Anti-Tirap Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected Tirap in human heart tissue.

Immunofluorescence Analysis: 10 µg/mL from a representative lot detected Tirap in human heart tissue.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology

Biochem/physiol Actions

This antibody recognizes the C-terminus of Tirap.

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected Tirap in 15 µg of human heart tissue lysate.
Control
Human heart tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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