biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... TIRAP(114609)
General description
Toll/interleukin-1 receptor domain-containing adapter protein (Tirap), also known as MyD88 adapter-like protein (Mal), contains one TIR domain that is involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection serving as an important link between the innate and adaptive immune responses.
~35 kDa observed
Immunogen
Epitope: C-terminus
KLH-conjugated linear peptide corresponding to the C-terminus of mouse Tirap.
Application
Detect Toll/interleukin-1 receptor domain-containing adapter protein using this rabbit polyclonal antibody, Anti-Tirap Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected Tirap in human heart tissue.
Immunofluorescence Analysis: 10 µg/mL from a representative lot detected Tirap in human heart tissue.
Immunofluorescence Analysis: 10 µg/mL from a representative lot detected Tirap in human heart tissue.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Immunoglobulins & Immunology
Biochem/physiol Actions
This antibody recognizes the C-terminus of Tirap.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected Tirap in 15 µg of human heart tissue lysate.
Western Blotting Analysis: 2 µg/mL of this antibody detected Tirap in 15 µg of human heart tissue lysate.
Control
Human heart tissue lysate
Human heart tissue lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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