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Merck
CN

ABS26

Anti-MNBH Antibody

from rabbit, purified by affinity chromatography

别名:

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, dual specificity tyrosine-phosphorylation-regulated kinase 1A, mnb protein kinase homolog hp86, Dual specificity YAK1-related kinase, serine/threonine kinase MNB, Protein kinase minibrain

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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biological source

rabbit

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, mouse

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

General description

Minibrain (MNBH) is also known as DYRK1 and is the human homolog of the mnb gene in Drosophila and is mapped on human chromosome 21q22.2, which is within the down syndrome critical region. MNBH may be involved in the signaling pathway that controls cell proliferation and is thought to regulate neuronal differentiation and apoptosis by phosphorylating Hip-1.
~86 kDa observed. Uncharacterized bands may be observed in some lysates.

Immunogen

GST-tagged recombinant protein corresponding to the N-terminus of human MNBH.

Application

Anti-MNBH Antibody is an antibody against MNBH for use in WB.

Biochem/physiol Actions

This antibody recognizes MNBH at the N-terminus.

Analysis Note

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected MNBH on 10 µg of NIH/3T3 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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存储类别

10-13 - German Storage Class 10 to 13

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