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Merck
CN

DX2091

Supelco

p-Dioxane

OmniSolv®

别名:

p-Dioxane, 1,4-Dioxane, 1

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关于此项目

线性分子式:
-O(CH2)2O(CH2)2-
CAS Number:
MDL编号:
UNSPSC代码:
12191504
EC索引号:
204-661-8
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蒸汽压

41 hPa ( 20 °C)

质量水平

产品线

OmniSolv®

方案

≥99.9% (GC)

表单

liquid

保质期

12 mo. (from manufacture date)

技术

HPLC: suitable
LC/MS: suitable
gas chromatography (GC): suitable

杂质

≤0.05% Water (H2O)
≤2 mg/L Peroxide (as H2O2)

蒸发残留物

≤1 mg/L

颜色

clear colorless,





折射率

n20/D 1.4206-1.4226

pH值(酸碱度)

6-8 (20 °C, 500 g/L in H2O)

沸点

101.5 °C/1013 hPa

mp

12 °C

转变温度

flash point 11 °C

密度

1.03 g/cm3 at 20 °C

UV cutoff

≤215 nm

紫外吸收

λ: 215 nm Amax: ≤1.00
λ: 250 nm Amax: ≤0.300
λ: 300 nm Amax: ≤0.020
λ: 350 nm Amax: ≤0.005
λ: 400 nm Amax: ≤0.005

运输

ambient

储存温度

no temp limit

SMILES字符串

O1CCOCC1

InChI

1S/C4H8O2/c1-2-6-4-3-5-1/h1-4H2

InChI key

RYHBNJHYFVUHQT-UHFFFAOYSA-N

一般描述

p-Dioxane, or 1,4-dioxane, is a cyclic organic compound that appears as a colorless, flammable liquid with a sweet odor. It is classified as a non-polar solvent and is widely used in various industrial applications because of its ability to dissolve a diverse range of organic compounds.

应用

OmniSolv®
p-dioxane is used as a solvent in
  • The synthesis of (Chloromethyl)dimethylphenylsilane from chloro(chloromethyl)dimethylsilane via zinc-catalyzed substitution reaction with phenylmagnesium bromide.
  • the synthesis of N-(2,2,2-trifluoro-1-hydroxyethyl)-acetamide from 2,2,2-trifluoro-1-methoxyethanol and acetamide.

包装

is packaged in 1L amber glass bottle
is packaged in 4L amber glass bottle

制备说明

Product filtered through a 0.2 μm filter

分析说明

Expiration dateExp 12 months from mfg dateAssay (GC)99.9% minBoiling range101-102°CEvaporation residue1mg/L maxFiltered through 0.2 µm filterTo pass testPeroxide (as H2O2)2mg/L maxRefractive index (n 20/D)1.4206-1.4226UV Abs. at 215 nm1.00AU maxUV Abs. at 250 nm0.300AU maxUV Abs. at 300 nm0.020AU maxUV Abs. at 350 nm0.005AU maxUV Abs. at 400 nm0.005AU maxUV Cut-off215nm maxWater (H2O)0.05% max

法律信息

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Carc. 1B - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

靶器官

Respiratory system

补充剂危害

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

51.8 °F - closed cup

闪点(°C)

11 °C - closed cup

法规信息

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Zinc-catalyzed nucleophilic substitution reaction of chlorosilanes with organomagnesium reagents
Murakami, Kei and Yorimitsu.et.al.
The Journal of Organic Chemistry, 74, 1415-1417 (2009)
Hydrogen-bonding interactions of norharmane in mixtures of acetic acid with benzene, p-dioxane and acetonitrile
Tapia, MJ and Reyman,et.al.
Physical Chemistry Chemical Physics, 4, 3676-3683 (2002)
Deconstructing noncovalent Kelch-like ECH-associated protein 1 (Keap1) inhibitors into fragments to reconstruct new potent compounds
Pallesen, Jakob S and Narayanan,et.al.
Journal of Medicinal Chemistry, 64, 4623-4661 (2021)

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