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Merck
CN

HI-MLSG

Human Insulin Kit

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
Technique(s):
radioimmunoassay: suitable
Detection method:
radioactive
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description

ED<sub>80</sub> = 7 ± 1 µU/ml ED<sub>50</sub> = 26 ± 3 µU/ml ED<sub>20</sub> = 102 ± 10 µU/ml , analytes available: Insulin, for protein analysis, 2-200 pg/mL (standard curve range)

feature

accuracy 93–100%

species reactivity

human

technique(s)

radioimmunoassay: suitable

UniProt accession no.

detection method

radioactive

Quality Level

General description

FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.

Application

Overnight, equilibrium incubation at room temperature. Sample volume = 100 µL serum, plasma, or tissue culture media

Analysis Note

Linearity 86–108%

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

法规信息

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