description
ED<sub>80</sub> = 7 ± 1 µU/ml ED<sub>50</sub> = 26 ± 3 µU/ml ED<sub>20</sub> = 102 ± 10 µU/ml , analytes available: Insulin, for protein analysis, 2-200 pg/mL (standard curve range)
feature
accuracy 93–100%
species reactivity
human
technique(s)
radioimmunoassay: suitable
UniProt accession no.
detection method
radioactive
Quality Level
General description
FUNCTION: SwissProt: P01308 # Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
SIZE: 110 amino acids; 11981 Da
SUBUNIT: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
SUBCELLULAR LOCATION: Secreted.
DISEASE:SwissProt: P01308 # Defects in INS are the cause of familial hyperproinsulinemia [MIM:176730].
SIMILARITY: SwissProt: P01308 ## Belongs to the insulin family.
Application
Overnight, equilibrium incubation at room temperature. Sample volume = 100 µL serum, plasma, or tissue culture media
Analysis Note
Linearity 86–108%
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
signalword
Danger
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - STOT RE 2
target_organs
Respiratory Tract
存储类别
10 - Combustible liquids
法规信息
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