biological source
rabbit
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
form
liquid
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, avoid repeated freeze/thaw cycles
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
Gene Information
human ... MTA3(57504)
General description
Immunoaffinity purified rabbit polyclonal antibody. Recognizes the ~62 kDa MTA3 protein.
Recognizes the ~62 kDa MTA3 protein in MCF-7 cells.
This Anti-MTA3 (400-450) Rabbit pAb is validated for use in Immunoblotting, Immunocytochemistry, Immunoprecipitation for the detection of MTA3 (400-450).
Immunogen
Human
a synthetic peptide corresponding to amino acids within residues 400-450 of human MTA3
Application
Immunoblotting (1:500-1:5000)
Immunocytochemistry (1:300)
Immunoprecipitation (2-10 g/mg lysate)
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Preparation Note
Following initial use, aliquot and freeze (-20°C) for long-term storage.
Analysis Note
Positive Control
MCF7 cells
MCF7 cells
Other Notes
Antibody should be titrated for optimal results in individual systems.
Fujita, N., et. al. 2003. Cell113, 207.
Kumar R. 2003. Cell113, 142.
Simpson, A, et.al. 2001. Gene273, 29.
Kumar R. 2003. Cell113, 142.
Simpson, A, et.al. 2001. Gene273, 29.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Highly Toxic (H)
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
The metastasis-associated gene MTA3 is an independent prognostic parameter in uterine non-endometrioid carcinomas.
Ioannis Mylonas et al.
Histopathology, 60(4), 665-670 (2012-01-13)
B Belinda Ding et al.
Journal of immunology (Baltimore, Md. : 1950), 190(4), 1827-1836 (2013-01-18)
After undergoing Ig somatic hypermutation and Ag selection, germinal center (GC) B cells terminally differentiate into either memory or plasma cells (PCs). It is known that the CD40L and IL-21/STAT3 signaling pathways play critical roles in this process, yet it
Jie Gao et al.
Cell death and differentiation, 28(9), 2818-2836 (2021-05-07)
The biological function of PRMT5 remains poorly understood in cervical cancer metastasis. Here, we report that PRMT5 physically associates with the transcription factor Snail and the NuRD(MTA1) complex to form a transcriptional-repressive complex that catalyzes the symmetrical histone dimethylation and