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Merck
CN

IM37

Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4)

liquid, clone 56-2A4, Calbiochem®

别名:

Anti-Gelatinase B, Anti-92 kDa Gelatinase, Anti-Matrix Metalloproteinase 9

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
56-2A4, monoclonal
Species reactivity:
human, rabbit, rat, guinea pig
Application:
Citations:
11
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biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

56-2A4, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human, rabbit, rat, guinea pig

should not react with

hamster, mouse, bovine

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(Frozen Sections
Immunoblotting (1 µg/mL)
Paraffin Sections )

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MMP9(4318)

General description

Purified mouse monoclonal antibody (see application references). Recognizes both the ~92 kDa latent and the ~83 kDa active forms of MMP-9.
Recognizes the ~92 kDa latent and the ~83 kDa active forms of MMP-9 in breast carcinoma tissue.
This Anti-MMP-9 (Ab-3) Mouse mAb (56-2A4) is validated for use in Frozen Sections, Immunoblotting, Paraffin Sections for the detection of MMP-9 (Ab-3).

Immunogen

Human
a synthetic peptide corresponding to amino acids 626-644 of human MMP-9

Application


Frozen Sections (see application references)
Immunoblotting (1 g/ml)
Paraffin Sections (see application references)

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 100 mM sodium phosphate buffer, 0.1% BSA, pH 7.0

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Negative Control
MMP-2 protein (Cat. Nos. PF023 or PF037)
Positive Control
MMP-9 protein (Cat. Nos. PF024 or PF038) or breast carcinoma tissue

Other Notes

Cottam, D.W. and Rees, R.C. 1993. Intl. J. Oncol.2, 861.
Stetler-Stevenson, W.G., et al. 1993. FASEB J.7, 1434.
Okada, Y., et al., 1992. J. Biol. Chem.267, 21712.
Woessner, J.F. 1991. FASEB J.5, 2145.
Liotta, L.A. and Stetler-Stevenson, W.G. 1990. in Seminars in Cancer Biology, ed. M.M. Gottesman. Vol. 1, 99.
This antibody does not react with MMP-1, MMP-2, MMP-3 or MMP-13. Antibody should be titrated for optimal results in individual systems.

Legal Information

Manufactured by Daiichi Fine Chemical Co., Ltd. Not available for sale in Japan.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Shinichiro Fujimoto et al.
Journal of the American College of Cardiology, 52(23), 1847-1857 (2008-11-29)
This study sought to evaluate the feasibility of noninvasive detection of matrix metalloproteinase (MMP) activity in experimental atherosclerosis using technetium-99m-labeled broad matrix metalloproteinase inhibitor (MPI) and to determine the effect of dietary modification and statin treatment on MMP activity. The
Fábio Montico et al.
Anatomical record (Hoboken, N.J. : 2007), 296(11), 1758-1767 (2013-10-10)
The influence of senescence and hormone replacement on the onset of pathologic processes in the prostate is not yet fully understood. The aim was to identify the immunoreactivity and protein levels of molecules involved in cell proliferation, tissue remodeling and
Satoru Ohshima et al.
Journal of the American College of Cardiology, 55(12), 1240-1249 (2010-03-20)
Technetium-99m-labeled matrix metalloproteinase inhibitor (MPI) was used for the noninvasive assessment of matrix metalloproteinase (MMP) activity in atherosclerotic plaques after minocycline (MC) intervention. MMP activity in atherosclerosis contributes to plaque instability. Some antimicrobial agents may attenuate MMP activity. Atherosclerotic lesions



全球贸易项目编号

货号GTIN
IM37-100UG07790788053796