biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
D1-4G2-4-15, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
isotype
IgG1, IgG2a
shipped in
dry ice
General description
黄病毒科的病毒是人类和兽医学中重要的节肢动物传播的病毒。它们通过蚊子和蜱传播，通常在自然界中维持在传播周期中。它们在人类中产生广泛的临床反应，从无症状的感染到暴发性脑炎或出血热。已知存在近60种黄病毒，但许多尚未证明会引起人类疾病。
Immunogen
登革热病毒2型抗原
Application
&已发表抗黄病毒组抗原抗体，克隆D1-4G2-4-15可检测黄病毒组抗原水平，&经验证可用于IF。
Biochem/physiol Actions
识别黄病毒组特异性抗原（登革热病毒、西尼罗河病毒、日本乙型脑炎、黄热病病毒、寨卡病毒等）。它与蛋白E结构域II末端的融合环结合。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
V Haridas et al.
PLoS neglected tropical diseases, 7(1), e2005-e2005 (2013-01-26)
Japanese encephalitis virus (JEV) is a major cause of viral encephalitis in South and South-East Asia. Lack of antivirals and non-availability of affordable vaccines in these endemic areas are a major setback in combating JEV and other closely related viruses
José A Aguilar-Briseño et al.
Nature communications, 11(1), 3177-3177 (2020-06-25)
Vascular permeability and plasma leakage are immune-pathologies of severe dengue virus (DENV) infection, but the mechanisms underlying the exacerbated inflammation during DENV pathogenesis are unclear. Here, we demonstrate that TLR2, together with its co-receptors CD14 and TLR6, is an innate
Marion Clé et al.
PLoS neglected tropical diseases, 14(4), e0008223-e0008223 (2020-04-24)
Usutu virus (USUV), an African mosquito-borne flavivirus closely related to West Nile virus, was first isolated in South Africa in 1959. USUV emerged in Europe two decades ago, causing notably massive mortality in Eurasian blackbirds. USUV is attracting increasing attention
Qian Chen et al.
Nature communications, 11(1), 2967-2967 (2020-06-13)
The recent outbreak of Zika virus (ZIKV) was associated with birth defects and pregnancy loss when maternal infection occurs in early pregnancy, but specific mechanisms driving placental insufficiency and subsequent ZIKV-mediated pathogenesis remain unclear. Here we show, using large scale
Pawan Kumar Singh et al.
The ocular surface, 17(3), 551-559 (2019-03-25)
Zika virus (ZIKV) has emerged as an important human pathogen causing ocular complications. There have been reports of the shedding of ZIKV in human as well as animal tears. In this study, we investigated the infectivity of ZIKV in corneal
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