biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
AHN-10, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable, immunoprecipitation (IP): suitable, radioimmunoassay: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SERP1(27230)
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Application
Anti-Neutrophil Elastase Antibody, clone AHN-10 detects level of Neutrophil Elastase & has been published & validated for use in IP, RIA & IC.
Immunoprecipitation
Immunocytochemistry
RIA
Optimal working dilutions must be determined by end user.
Immunocytochemistry
RIA
Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
Inflammation & Autoimmune Mechanisms
Biochem/physiol Actions
Reacts specifically with human neutrophil elastase and not with the 3 homologous neutrophil neutral serine proteases, cathepsin G, esterase N and proteinase 3. Inhibits the elastinolytic activity of elastase. Elastase is felt to play an important role in a number of disease states.
Preparation Note
Maintain in convenient aliquots at -20°C or colder for up to 12 months. Avoid thawing and refreezing.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
M Brittany Johnson et al.
Cellular microbiology, 17(5), 648-665 (2014-10-28)
During gonorrhoeal infection, there is a heterogeneous population of Neisseria gonorrhoeae (Gc) varied in their expression of opacity-associated (Opa) proteins. While Opa proteins are important for bacterial attachment and invasion of epithelial cells, Opa+ Gc has a survival defect after
E Jimenez Flores et al.
Infection and immunity, 85(7) (2017-04-26)
Peptoanaerobacter stomatis is a newly appreciated taxon associated with periodontal diseases; however, little is known about the organism's pathogenic potential or its interaction with the host immune response. Neutrophils are the most abundant innate immune cell present in the gingival
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