MAB1954
Anti-Integrin α4 Antibody, clone P4G9
ascites fluid, clone P4G9, Chemicon®
别名:
CD49d
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
P4G9, monoclonal
Application:
immunohistochemistry
Species reactivity:
human
Citations:
8
Technique(s):
immunohistochemistry: suitable
Uniprot accession no.:
产品名称
Anti-Integrin α4 Antibody, clone P4G9, ascites fluid, clone P4G9, Chemicon®
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
P4G9, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA4(3676)
Preparation Note
Store at -20 °C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Application
Detect Integrin α4 using this Anti-Integrin α4 Antibody, clone P4G9 validated for use in IH.
Immunocytochemistry on Jurkat cells at 1:1,600.
Inhibits attachment of hematopoeitic cells and fibroblasts to fibronectin (note: sodium azide should be removed prior to attachment assay).
Optimal working dilutions must be determined by the end user.
Inhibits attachment of hematopoeitic cells and fibroblasts to fibronectin (note: sodium azide should be removed prior to attachment assay).
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Human integrin alpha4. The alpha4beta1 integrin receptor recognizes an RGD-independent alternative adhesion site in the CS-1 region of fibronectin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Other Notes
Replaces: 04-1131
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
A New alpha5beta1 integrin-dependent survival pathway through GSK3beta activation in leukemic cells.
Fabienne De Toni-Costes et al.
PloS one, 5(3), e9807-e9807 (2010-03-31)
Cell survival mediated by integrin engagement has been implicated in cell adhesion-mediated drug resistance. We have recently demonstrated that the activation of glycogen synthase kinase 3 beta (GSK3beta) is a new pathway supporting the chemoresistance of leukemic cells adhered to
Ming-Yi Lee et al.
PloS one, 4(10), e6913-e6913 (2009-10-23)
Human placental multipotent mesenchymal stromal cells (hPMSCs) can be isolated from term placenta, but their angiogenic ability and the regulatory pathways involved are not known. hPMSCs were shown to express integrins alpha(v), alpha(4), alpha(5), beta(1), beta(3), and beta(5) and could
Barbara Garmy-Susini et al.
The Journal of clinical investigation, 115(6), 1542-1551 (2005-05-20)
Neovascularization depends on vascular cell proliferation and on the stabilization of vessels by association of vascular smooth muscle-like pericytes with ECs. Here we show that integrin alpha4beta1 (VLA-4) and VCAM-1 promote close intercellular adhesion between ECs and pericytes and that
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