生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
P4H9, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunohistochemistry: suitable
同位素/亚型
IgG3
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... ITGB2(3689)
应用
Anti-Integrin β2 Antibody, clone P4H9, azide free detects level of Integrin β2 & has been published & validated for use in IH.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Suitable for use in immunofluorescence.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
Also suitable for aggregation inhibition assays using hematopoeitic cells or EBV-transformed B lymphocytes.
For extensive dilution, protein-containing or other stabilizing medium should be used. Final working dilutions must be determined by end user.
生化/生理作用
beta2 integrin on hematopoeitic cells. Not present on platelets, endothelial cells, epithelial cells or fibroblasts.
外形
Format: Purified
Sterile-filtered liquid containing no preservatives.
制备说明
Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
Hee Doo Lee et al.
European journal of immunology, 44(4), 1156-1169 (2013-12-18)
Integrin trafficking, including internalization, recycling, and lysosomal degradation, is crucial for the regulation of cellular functions. Exosomes, nano-sized extracellular vesicles, are believed to play important roles in intercellular communications. This study demonstrates that exosomes released from human macrophages negatively regulate
Vira V Artym et al.
The Journal of cell biology, 208(3), 331-350 (2015-02-04)
Cell interactions with the extracellular matrix (ECM) can regulate multiple cellular activities and the matrix itself in dynamic, bidirectional processes. One such process is local proteolytic modification of the ECM. Invadopodia of tumor cells are actin-rich proteolytic protrusions that locally
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