MAB2015
Anti-Aggrecan Antibody
CHEMICON®, mouse monoclonal, EFG-4
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关于此项目
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
EFG-4, monoclonal
Species reactivity:
bovine, canine, pig, chicken, human, sheep, rabbit
Application:
ELISA, IHC, RIA, WB
Citations:
18
产品名称
Anti-Cartilage Proteoglycan Antibody, adult, clone EFG-4, ascites fluid, clone EFG-4, Chemicon®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
EFG-4, monoclonal
species reactivity
bovine, canine, pig, chicken, human, sheep, rabbit
should not react with
rat, mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable, radioimmunoassay: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... ACAN(176)
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Immunogen
Epitope: adult
Human adult cartilage proteoglycan.
Application
Anti-Cartilage Proteoglycan Antibody, adult, clone EFG-4 detects level of Cartilage Proteoglycan & has been published & validated for use in ELISA, RIA, WB, IH.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Western blot: 1:1,00 - 1:200
Immunohistochemistry: 1:50 - 250
ELISA: 1:250 - 1: 2500
RIA: 1:20,000 - 1:40,000
Optimal working dilutions must be determined by the end user.I/
Immunohistochemistry: 1:50 - 250
ELISA: 1:250 - 1: 2500
RIA: 1:20,000 - 1:40,000
Optimal working dilutions must be determined by the end user.I/
Biochem/physiol Actions
Recognizes the short peptides substituted with keratan sulfate side chains and within the core protein of proteoglycans in articular cartilages, chicken limb bud and cornea. Does not cross-react with human fetal cartilage proteoglycans.
Physical form
Ascites fluid
Preparation Note
Maintain at -20°C in aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Daniela A Frauchiger et al.
Tissue engineering. Part C, Methods, 25(10), 571-580 (2019-06-04)
Low back pain related to intervertebral disk (IVD) degeneration has a major socioeconomic impact on our aging society. Therefore, stem cell therapy to activate self-repair of the IVD remains an exciting treatment strategy. In this respect, tissue-specific progenitors may play
Adel Tekari et al.
Stem cell research & therapy, 7(1), 75-75 (2016-05-25)
The intervertebral disc (IVD) has limited self-healing potential and disc repair strategies require an appropriate cell source such as progenitor cells that could regenerate the damaged cells and tissues. The objective of this study was to identify nucleus pulposus-derived progenitor
T Nukaga et al.
European cells & materials, 31, 95-106 (2016-01-28)
Transplantation of activated nucleus pulposus (NP) cells obtained by coculturing NP cells and bone marrow mesenchymal stromal cells having cell-to-cell contact has been shown to be effective in animal models and, more recently, in human clinical trials. If the NP
C Manferdini et al.
Journal of tissue engineering and regenerative medicine, 10(5), 374-391 (2013-03-16)
Osteochondral lesions require treatment to restore the biology and functionality of the joint. A novel nanostructured biomimetic gradient scaffold was developed to mimic the biochemical and biophysical properties of the different layers of native osteochondral structure. The present results show
Constanze Buhrmann et al.
Arthritis research & therapy, 12(4), R127-R127 (2010-07-03)
Osteoarthritis (OA) and rheumatoid arthritis (RA) are characterised by joint inflammation and cartilage degradation. Although mesenchymal stem cell (MSC)-like progenitors are resident in the superficial zone of articular cartilage, damaged tissue does not possess the capacity for regeneration. The high
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