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Merck
CN

MAB2146Z

Anti-ICAM-1 Antibody, clone P2A4, Azide Free

clone P2A4, Chemicon®, from mouse

别名:

CD54, MAB2146

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
P2A4, monoclonal
Application:
ELISA
flow cytometry
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
Species reactivity:
human
Citations:
7
Technique(s):
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
Uniprot accession no.:
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产品名称

Anti-ICAM-1 Antibody, clone P2A4, Azide Free, clone P2A4, Chemicon®, from mouse

antibody product type

primary antibodies

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

clone

P2A4, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ICAM1(3383)

Application

Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue

Immunocytochemistry: for use on B cells, PBL, T cells

Immunoprecipitation

FACS

ELISA

Inhibits ICAM-1 dependent adhesive interactions

Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)
This Anti-ICAM-1 Antibody, clone P2A4, Azide Free is validated for use in ELISA, FC, IP, IC, IH, FUNC for the detection of ICAM-1.

Biochem/physiol Actions

Human ICAM-1

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

IL-1beta activated HUVEC (human)

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Sterile-filtered lquid containing 0.2M phosphate buffer, 0.25M sodium chloride, no preservatives.

Preparation Note

Maintain at -20°C.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Kelly M Bailey et al.
Oncotarget, 10(36), 3385-3399 (2019-06-06)
Metastatic and relapsed Ewing sarcoma typically afflicts the adolescent population and is largely fatal. These bone tumors are most commonly driven by the fusion oncoprotein EWS-FLI1. Ewing tumors demonstrate significant intra-tumoral heterogeneity, and individual tumor cells can express highly variable
LFA-1 and ICAM-1 expression induced during melanoma-endothelial cell co-culture favors the transendothelial migration of melanoma cell lines in vitro.
Ghislin, S; Obino, D; Middendorp, S; Boggetto, N; Alcaide-Loridan, C; Deshayes, F
BMC Cancer null
Mario C Manresa et al.
Gastroenterology, 159(5), 1778-1792 (2020-07-28)
Eosinophilic esophagitis (EoE) is an antigen-mediated eosinophilic disease of the esophagus that involves fibroblast activation and progression to fibrostenosis. Cytokines produced by T-helper type 2 cells and transforming growth factor beta 1 (TGFβ1) contribute to the development of EoE, but

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