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Merck
CN

MAB2223

抗DNP抗体,克隆9H8.1

clone 9H8.1, from mouse

别名:

Dinitrophenol

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
9H8.1, monoclonal
Technique(s):
western blot: suitable
Application:
western blot
Citations:
13
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产品名称

抗DNP抗体,克隆9H8.1, clone 9H8.1, from mouse

biological source

mouse

antibody form

purified immunoglobulin

clone

9H8.1, monoclonal

species reactivity (predicted by homology)

all

technique(s)

western blot: suitable

isotype

IgG1κ

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Analysis Note

对照
Oxyblot蛋白质标准品
通过蛋白质印迹在Oxyblot蛋白质标准品中进行了评估。

蛋白质印迹分析:0.5 µg/mL的该抗体在10 µg Oxyblot蛋白质标准品中检测到DNP。

Application

该抗-DNP抗体,克隆9H8.1经过验证可用于WB中的DNP检测。

Biochem/physiol Actions

已证明可与更广泛的物种中的DNP部分反应。 预期该抗体′反应性与物种无关。

General description

二硝基苯酚(DNP)是一种小的水溶性疏水配体,可在酸性pH值作用下与运甲状腺素蛋白结合,并减少淀粉样原纤维的形成。100 mg/L或更高的DNP水平对适应的细菌有很大的毒性。DNP与神经退行性疾病和神经系统疾病的可能疗法有关。
观察到各种kDa。 使用Oxyblot蛋白标准品(S7151)检验该抗体。 这些标准品是磷酸化酶B,BSA,OVA,碳酸酐酶和胰蛋白酶抑制剂,每个蛋白含有1-3个DNP残基。

Immunogen

KLH结合的DNP

Physical form

形式:纯化

存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Jennifer B M Steffen et al.
The Journal of experimental biology, 226(15) (2023-07-20)
Coastal environments commonly experience fluctuations in salinity and hypoxia-reoxygenation (H/R) stress that can negatively affect mitochondrial functions of marine organisms. Although intertidal bivalves are adapted to these conditions, the mechanisms that sustain mitochondrial integrity and function are not well understood.
Linda Adzigbli et al.
Scientific reports, 14(1), 9658-9658 (2024-04-27)
Sessile benthic organisms like oysters inhabit the intertidal zone, subject to alternating hypoxia and reoxygenation (H/R) episodes during tidal movements, impacting respiratory chain activities and metabolome compositions. We investigated the effects of constant severe hypoxia (90 min at ~ 0% O2 ) followed
Lona Zeneyedpour et al.
International journal of molecular sciences, 23(9) (2022-05-15)
We investigated the feasibility of detecting the presence of specific autoantibodies against potential tumor-associated peptide antigens by enriching these antibody-peptide complexes using Melon Gel resin and mass spectrometry. Our goal was to find tumor-associated phospho-sites that trigger immunoreactions and raise
Rita Araújo et al.
Bone, 158, 116355-116355 (2022-02-14)
Diabetes mellitus (DM) embrace a group of chronic metabolic conditions with a high morbidity, causing deleterious effects in different tissues and organs, including bone. Hyperglycemia seems to be one of the most contributing etiological factors of bone-related alterations, altering metabolic
Brígida R Pinho et al.
Free radical biology & medicine, 146, 372-382 (2019-11-22)
Abnormal protein homeostasis (proteostasis), dysfunctional mitochondria, and aberrant redox signalling are often associated in neurodegenerative disorders, such as Huntington's (HD), Alzheimer's and Parkinson's diseases. It remains incompletely understood, however, how changes in redox signalling affect proteostasis mechanisms, including protein degradation

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