MAB5416
抗-谷氨酸受体3抗体，克隆3B3
clone 3B3, Chemicon®, from mouse
别名:
AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3
生物来源
mouse
质量水平
偶联物
unconjugated
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
3B3, monoclonal
种属反应性
monkey, mouse, human
种属反应性（根据同源性预测）
rat
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
同位素/亚型
IgG1κ
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... GRIA3(2892)
一般描述
AMPA受体介导大多数兴奋性突触的快速突触电流，化学计量以亚型组成为特征。AMPA选择性GluR亚基有四种类型（GluR1、GluR2、GluR3和GluR4）。不同亚基的四聚体或五聚体组合有助于AMPA受体的功能多样性。 从突触后膜插入或去除GluR1/GluR4寡聚通道似乎是LTP/LTD活性依赖性的，而GluR2/GluR3寡聚体不断循环。 Millipore’s抗GluR2/3抗体可用于定位PSD中GluR2/GluR3受体装配体的表达。
约110 kDa
免疫原
融合蛋白，GluR3的N末端
应用
免疫组织化学： 一个先前批次的该抗体被用于IH。
最佳工作稀释度必须由最终用户确定。
最佳工作稀释度必须由最终用户确定。
抗谷氨酸受体3抗体，克隆3B3是用于WB、IC、IH、IH(P)的抗谷氨酸受体3的抗体。
生化/生理作用
与谷氨酸受体3（GluR3）反应。与GluR2无交叉反应。
外形
形式：纯化
溶于PBS中的液体。不含防腐剂。
分析说明
对照
脑
海马组织
脑
海马组织
蛋白质印迹分析： 该抗体的一个先前批次被用于WB。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
David Bartolomé-Martín et al.
Journal of cell science, 125(Pt 2), 422-434 (2012-02-15)
Following the exocytosis of neurotransmitter-containing synaptic vesicles, endocytosis is fundamental to re-establishing conditions for synaptic transmission. As there are distinct endocytotic pathways that each differ in their efficiency to generate releasable synaptic vesicles, we used the dye FM1-43 to track
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.
Tucholski, J; Pinner, AL; Simmons, MS; Meador-Woodruff, JH
Testing null
Xiu Sun et al.
The European journal of neuroscience, 30(4), 539-550 (2009-08-14)
Synaptic scaling has been proposed as a form of plasticity that may contribute to drug addiction but it has not been previously demonstrated in the nucleus accumbens (NAc), a critical region for addiction. Here we demonstrate bidirectional synaptic scaling in
B Borroni et al.
Scientific reports, 7(1), 6723-6723 (2017-07-29)
Frontotemporal Dementia (FTD) is a neurodegenerative disorder mainly characterised by Tau or TDP43 inclusions. A co-autoimmune aetiology has been hypothesised. In this study, we aimed at defining the pathogenetic role of anti-AMPA GluA3 antibodies in FTD. Serum and cerebrospinal fluid
Janusz Tucholski et al.
Schizophrenia research, 146(1-3), 177-183 (2013-03-07)
Numerous studies have demonstrated brain region- and subunit-specific abnormalities in the expression of subunits of the AMPA subtype of glutamate receptors in schizophrenia. In addition, abnormalities in the expression of proteins that regulate the forward trafficking of AMPA receptors through
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持