产品名称
Anti-Choline Transporter Antibody, clone 62-2E8, ascites fluid, clone 62-2E8, Chemicon®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
62-2E8, monoclonal
species reactivity
human, mouse
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SLC5A7(60482)
Application
Detect Choline Transporter using this Anti-Choline Transporter Antibody, clone 62-2E8 validated for use in IC, IH & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot. The antibody detects a 65 kDa band in mouse brain tissue lysate. The CHT immunoreactivity was most abundant in the striatum.
Immunohistochemistry 1:2,000 - 1:8,000
Immunocytochemistry
Optimal working dilutions must be determined by end user.
Immunohistochemistry 1:2,000 - 1:8,000
Immunocytochemistry
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Hemicholinium-3-sensitive choline transporter (CHT).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Recombinant protein from the C-terminus of human CHT.
Physical form
Ascites fluid. Liquid. Contains no preservative.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Anthony C Wong et al.
Journal of virology, 84(1), 163-175 (2009-10-23)
Ebolavirus (EBOV) entry into cells requires proteolytic disassembly of the viral glycoprotein, GP. This proteolytic processing, unusually extensive for an enveloped virus entry protein, is mediated by cysteine cathepsins, a family of endosomal/lysosomal proteases. Previous work has shown that cleavage
Vinay Parikh et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(6), 2326-2337 (2013-02-09)
Functional variation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-deficit/hyperactivity disorder. Here, we report that a heterozygous deletion in the CHT gene in mice (CHT(+/-)) limits the capacity of cholinergic neurons to sustain acetylcholine
A V Terry et al.
Neuroscience, 146(3), 1316-1332 (2007-04-17)
First and second generation antipsychotics (FGAs and SGAs) ameliorate psychotic symptoms of schizophrenia, however, their chronic effects on information processing and memory function (i.e. key determinants of long term functional outcome) are largely unknown. In this rodent study the effects
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