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Merck
CN

MAB5514

Anti-Choline Transporter Antibody, clone 62-2E8

ascites fluid, clone 62-2E8, Chemicon®

别名:

CHT

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
62-2E8, monoclonal
Species reactivity:
human, mouse
Application:
ICC, IHC, WB
Citations:
3
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biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

62-2E8, monoclonal

species reactivity

human, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SLC5A7(60482)

Immunogen

Recombinant protein from the C-terminus of human CHT.

Application

Detect Choline Transporter using this Anti-Choline Transporter Antibody, clone 62-2E8 validated for use in IC, IH & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot. The antibody detects a 65 kDa band in mouse brain tissue lysate. The CHT immunoreactivity was most abundant in the striatum.

Immunohistochemistry 1:2,000 - 1:8,000

Immunocytochemistry

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Hemicholinium-3-sensitive choline transporter (CHT).

Physical form

Ascites fluid. Liquid. Contains no preservative.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Anthony C Wong et al.
Journal of virology, 84(1), 163-175 (2009-10-23)
Ebolavirus (EBOV) entry into cells requires proteolytic disassembly of the viral glycoprotein, GP. This proteolytic processing, unusually extensive for an enveloped virus entry protein, is mediated by cysteine cathepsins, a family of endosomal/lysosomal proteases. Previous work has shown that cleavage
Vinay Parikh et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(6), 2326-2337 (2013-02-09)
Functional variation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-deficit/hyperactivity disorder. Here, we report that a heterozygous deletion in the CHT gene in mice (CHT(+/-)) limits the capacity of cholinergic neurons to sustain acetylcholine
A V Terry et al.
Neuroscience, 146(3), 1316-1332 (2007-04-17)
First and second generation antipsychotics (FGAs and SGAs) ameliorate psychotic symptoms of schizophrenia, however, their chronic effects on information processing and memory function (i.e. key determinants of long term functional outcome) are largely unknown. In this rodent study the effects



全球贸易项目编号

货号GTIN
MAB551404053252360718