产品名称
抗人偏肺病毒抗体，克隆号36, clone 36, Chemicon®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
36, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
isotype
IgG2a
shipped in
wet ice
Quality Level
Application
使用该抗人类偏肺病毒抗体（克隆号36）检测人类偏肺病毒，经验证可用于ELISA、FC & IF。
研究子类别
传染病 - 病毒
传染病 - 病毒
研究类别
传染病
传染病
Biochem/physiol Actions
对核蛋白有特异性。与所有亚型（A1、A2、B1、B2）均有反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
人类偏肺病毒（hMPV）是副粘病毒亚科肺炎病毒属的一员，2001年首次在荷兰儿科呼吸道标本中检出。 它是一种有包膜的多形性病毒，基因组为单股负链RNA。目前已检出两种主要血清型：A 型和 B 型。几项研究在世界各地的标本中发现了hMPV，据估计，到5岁时，70% 的儿童将产生hMPV抗体。
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
形式：纯化
液体形式，溶于0.02M PB和0.25M NaCl（pH 7.6）中。含0.1%叠氮化钠。
Preparation Note
自接收之日起，可在2°-8°C下储存长达12个月。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Kathleen M Nitschinsk et al.
Intervirology, 61(3), 149-154 (2018-08-27)
Human metapneumovirus (hMPV) is an important human respiratory pathogen and is implicated in an array of respiratory illnesses, ranging from asymptomatic infection to severe bronchiolitis. Currently, there is no reliable vaccine or specific antiviral therapy for hMPV infection and treatment
Fernando Villalón-Letelier et al.
mBio, 12(5), e0148421-e0148421 (2021-09-15)
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible MARCH8 expression, we show that MARCH8 did not alter susceptibility to influenza A virus (IAV)
Leah Gillespie et al.
Journal of virology, 90(17), 7848-7863 (2016-06-24)
It is well established that glycosaminoglycans (GAGs) function as attachment factors for human metapneumovirus (HMPV), concentrating virions at the cell surface to promote interaction with other receptors for virus entry and infection. There is increasing evidence to suggest that multiple
Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy.
Maggi, Fabrizio, et al.
Journal of Clinical Microbiology, 41, 2987-2991 (2003)
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