产品名称
Anti-Papillomavirus Antibody, 2-17, clone TVG 261, clone TVG 261, Chemicon®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
clone
TVG 261, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
isotype
IgG1
shipped in
wet ice
Quality Level
Application
Anti-Papillomavirus Antibody, 2-17, clone TVG 261 detects level of Papillomavirus & has been published & validated for use in ELISA & WB.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Western Blot
ELISA
Optimal dilutions must be determined by end user
ELISA
Optimal dilutions must be determined by end user
Biochem/physiol Actions
HPV-16-E2, aa 2-17 of human papilloma virus type 16-E2. ETLCQRLNVCQDKILT
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The HPV family of DNA tumor viruses includes HPV-16 and is associated with a large portion of cervical cancer cases.
Immunogen
Epitope: 2-17
Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Purified immunoglobulin. Liquid 0.02M PB, 0.25M NaCl, pH 7.6 buffer containing 0.1% sodium azide as a preservative.
Preparation Note
Store at 2 to 8°C for up to 12 months from date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Hibma, M H, et al.
European Journal of Biochemistry, 229, 517-525 (1995)
E Z Tchilian et al.
Journal of immunology (Baltimore, Md. : 1950), 166(2), 1308-1313 (2001-01-06)
SCID is a heterogeneous group of hereditary diseases. Mutations in the common gamma-chain (gamma(c)) of cytokine receptors, including those for IL-2, IL-4, IL-7, IL-9, and IL-15, are responsible for an X-linked form of the disease, while mutations of several other
Martha Luevano et al.
Virology, 405(1), 31-40 (2010-06-18)
We have developed microarrays with all eight proteins encoded by 13 different human papillomavirus types associated with anogenital cancer (HPV-16, -18, -31, -33, -35, -45, and -53), genital warts (HPV-6 and -11), or skin lesions (HPV-1, -2, -4, and -5).
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