MABD24A4
Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor™ 488 conjugate
clone 7F7.1, from mouse, ALEXA FLUOR™ 488
别名:
Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog
产品名称
Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor™ 488 conjugate, clone 7F7.1, from mouse, ALEXA FLUOR™ 488
biological source
mouse
conjugate
ALEXA FLUOR™ 488
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
7F7.1, monoclonal
species reactivity
human
technique(s)
immunocytochemistry: suitable
isotype
IgG2a
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... NANOG(79923)
Analysis Note
Evaluated by Immunocytochemistry in H9 human embryonic stem cells. Immunocytochemsitry Analysis: A 1:100 dilution of this antibody detected NANOG in H9 human embryonic stem cells.
Application
Anti-NANOG Antibody, clone 7F7.1, Alexa Fluor 488 conjugate.
General description
NANOG (Homeobox protein NANOG) is a member of the Nanog homeobox family of DNA-binding proteins. It is expressed in embryonic stem cells and confers pluripotency on these cells. Once embryonic stem cells become differentiated, NANOG expression is suppressed. NANOG is involved in the Hedgehog/Gli1 signaling pathway which has been implicated in the development and growth of various types of tumors. NANOG has also been identified as a key transcription factor used to generate induced pluripotent stem cells.
The uncojugated parent antibody (Catalog No. MABD24) has an observed MW of 39 kDa
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Purified mouse monoclonal IgG2a conjugated to Alexa Fluor™ 488 in PBS with 0.1% sodium azide and 15mg/ml BSA.
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Breanna S Borys et al.
Stem cell research & therapy, 12(1), 55-55 (2021-01-14)
Human induced pluripotent stem cells (hiPSCs) hold enormous promise in accelerating breakthroughs in understanding human development, drug screening, disease modeling, and cell and gene therapies. Their potential, however, has been bottlenecked in a mostly laboratory setting due to bioprocess challenges
Breanna S Borys et al.
Stem cells translational medicine, 9(9), 1036-1052 (2020-05-24)
Human induced pluripotent stem cells (hiPSCs) have generated a great deal of attention owing to their capacity for self-renewal and differentiation into the three germ layers of the body. Their discovery has facilitated a new era in biomedicine for understanding
Victor J T Lin et al.
Scientific reports, 7(1), 5005-5005 (2017-07-12)
Despite their well-known function in maintaining normal cell physiology, how inorganic elements are relevant to cellular pluripotency and differentiation in human pluripotent stem cells (hPSCs) has yet to be systematically explored. Using total reflection X-ray fluorescence (TXRF) spectrometry and inductively
Quan Qi et al.
International journal of molecular medicine, 35(3), 569-578 (2014-12-20)
The present study aimed to investigate the X chromosome inactivation (XCI) status in long-term cultured human parthenogenetic embryonic stem cells. One human embryonic stem (hES) cell line and 2 human parthenogenetic embryonic stem (hPES) cell lines were subjected to long-term
Melissa Conti Mazza et al.
Stem cell research, 55, 102506-102506 (2021-08-23)
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