40 kDa calculated

His-tagged recombinant protein corresponding to human FPR1 near the C-terminus.

Epitope: Near C-terminus

Clone NFPRb selectively detects FPR1 with non-phosphorylated C-terminal tail. Diminished immunoreactivity is an indication of enhanced FPR1 C-terminal tail phosphorylation or neutrophils activation. Clone NFPRb is not reactive toward N-formyl peptide receptor 2 (encoded by FPR2/FPRL1 gene) regardless of its phosphorylation state (PMID 16675446, 17675514, 23873933).

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 1.5 µg of this antibody detected FPR1 in human peripheral blood mononuclear.

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