Anti-CD8a (mouse) Antibody, Alexa Fluor^™647, clone 53-6.7

T-cell surface glycoprotein CD8 alpha chain, also known as T-cell surface glycoprotein Lyt-2 or CD8a or CD8a, is a member of the immunoglobulin superfamily acting as a co-receptor with MHC class I-restricted T cell receptors, and through its association with protein tyrosine kinase p56Ick, modulates antigen recognition and T cell activation as well as thymic development. CD8a is expressed on the majority of thymocytes, a subset of mature T lymphocytes, and NK cells (almost exclusively CD8a homodimers).

27 kDa calculated

Anti-CD8a (mouse) Antibody, AlexaFluor647, clone 53-6.7 is a highly specific rat monoclonal antibody, that targets CD8 & has been tested in Flow Cytometry, IHC & IP.

The antibody was purified by affinity chromatography, and conjugated with AlexaFluor488 under optimal conditions. The solution is free of unconjugated AlexaFluor488 and unconjugated antibody. Alexa Fluor is a registered trademark of Molecular Probes, Inc. Alexa Fluor dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.

Flow Cytometry Analysis: 0.25 μg of this antibody detected CD8a in one million C57BL/6 mouse splenocytes.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

ALEXA FLUOR is a trademark of Life Technologies