biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
4H6.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SLC22A3(6581)
General description
Solute carrier family 22 member 3 (UniProt O75751; also known as EMT, Extraneuronal monoamine transporterorganic cation transporter 3, Organic cation transporter 3) is encoded by the SLC22A3 (also known as EMTH, OCT3) gene (Gene ID 6581) in human. Solute carrier family 22 member 3 is a multi-transmembrane protein that mediates the outward transport and clearance of endogenous small organic cations as well as a wide array of drugs and environmental toxins. Known substrates for this transporter include histamine, serotonin, norepinephrine, dopamine and MPP+.
~70 kDa observed. Due to glycosylation, the target band appears larger than the calculated molecular weight of 61.3 kDa
Immunogen
Epitope: C-terminal
GST-tagged recombinant protein corresponding to the C-terminal of human SLC22A3.
Application
Anti-SLC22A3 Antibody, clone 4H6.1, Cat. No. MABN359, is a highly specific mouse monoclonal antibody, that targets SLC22A3 and has been tested in Western Blotting.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in human brain tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SLC22A3 in 10 µg of human brain tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SLC22A3 in 10 µg of human brain tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
Replaces: MABN1039
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable