偶联物
unconjugated
抗体形式
purified antibody
克隆
1009
monoclonal
纯化方式
using protein G
种属反应性
human, rat, mouse
浓度
(Please refer to lot specific datasheet.)
技术
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
radioimmunoassay: suitable
western blot: suitable
同位素/亚型
IgG1κ
UniProt登记号
作用机制
| inhibits
靶向翻译后修饰
unmodified
一般描述
Recombinant fragment corresponding to 241 amino acids corresponding to six EGF repeats from human Thrombomodulin.
~60.33 kDa calculated.
应用
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Thrombomodulin in human tonsil tissue sections.
ELISA Analysis: A representative lot detected Thrombomodulin in ELISA applicaitons (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Radioimmunoassay Analysis: A representative lot detected Thrombomodulin in Radioimmunoassay applications (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Inhibits Activity/Function Analysis: A representative lot of this blocked thrombin binding and reduced Protein C activation (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6).
Flow Cytometry Analysis: A representative lot detected Thrombomodulin in Flow Cytometry applications (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Western Blotting Analysis: A representative lot detected Thrombomodulin in Western Blotting applications. (Xu, J., et. al. (1999). J Biol Chem. 274(10):6704-10; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Immunocytochemistry Analysis: A representative lot detected Thrombomodulin in Immunocytochemistry applications (Campbell, J.E., et. al. (2010). Blood. 116(26):6082-91).
Immunohistochemistry (Paraffin) Analysis: A representative lot detected Thrombomodulin in Immunohistochemistry applications (Trotman, W.E., et. al. (2011). Histochem Cell Biol. 135(2):141-52).
ELISA Analysis: A representative lot detected Thrombomodulin in ELISA applicaitons (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Radioimmunoassay Analysis: A representative lot detected Thrombomodulin in Radioimmunoassay applications (Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Inhibits Activity/Function Analysis: A representative lot of this blocked thrombin binding and reduced Protein C activation (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6).
Flow Cytometry Analysis: A representative lot detected Thrombomodulin in Flow Cytometry applications (Stearns-Kurosawa, D.J., et. al. (1996). Proc Natl Acad Sci USA. 93(19):10212-6; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Western Blotting Analysis: A representative lot detected Thrombomodulin in Western Blotting applications. (Xu, J., et. al. (1999). J Biol Chem. 274(10):6704-10; Woodley-Cook, J., et. al. (2006). Mol Cancer Ther. 5(12):3303-11).
Immunocytochemistry Analysis: A representative lot detected Thrombomodulin in Immunocytochemistry applications (Campbell, J.E., et. al. (2010). Blood. 116(26):6082-91).
Immunohistochemistry (Paraffin) Analysis: A representative lot detected Thrombomodulin in Immunohistochemistry applications (Trotman, W.E., et. al. (2011). Histochem Cell Biol. 135(2):141-52).
生化/生理作用
Clone 1009 is a mouse monoclonal antibody that detects Thrombomodulin.
外形
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
制备说明
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Evaluated by Immunohistochemistry (Paraffin) in human placenta tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Thrombomodulin in human placenta tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Thrombomodulin in human placenta tissue sections.
其他说明
Human, Rat.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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