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Merck
CN

MABS2160

Anti-NARC-1 (PCSK9) Antibody, clone 13D3

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
13D3, monoclonal
Application:
ELISA, WB
Citations:
-
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conjugate

unconjugated

antibody form

purified antibody

clone

13D3, monoclonal

purified by

using protein G

concentration

(Please refer to lot specific datasheet.)

technique(s)

ELISA: suitable, western blot: suitable

isotype

IgG1κ

UniProt accession no.

target post-translational modification

unmodified

species reactivity

mouse

General description

Full-length purified human Proprotein convertase 9 (PCSK9).
~75 and 59 kDa observed (proprotein and cleaved form); 74.29 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Application

Western Blotting Analysis: A representative lot detected NARC-1 (PCSK9) in Western Blotting applications (Zhang, D.W., et. al. (2008). Proc Natl Acad Sci USA. 105(35):13045-50; Laggace, T.A., et. al. (2006). J Clin Invest. 116(11):2995-3005).

ELISA Analysis: A representative lot detected NARC-1 (PCSK9) in ELISA applications (Laggace, T.A., et. al. (2006). J Clin Invest. 116(11):2995-3005; Lakoski, S.G., et. al. (2009). J Clin Endocrinol Metab. 94(7):2537-43).

Biochem/physiol Actions

Clone 13D3 is a mouse monoclonal antibody that specifically detects Proprotein convertase 9 (NARC-1) and its cleaved form in human cells.

Physical form

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in HepG2 cell lysates.

Western Blotting Analysis: 1 µg/mL of this antibody detected NARC-1 (PCSK9) in HepG2 cell lysates.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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