Anti-NARC-1 (PCSK9) Antibody, clone 15A6

Full-length purified human Proprotein convertase 9 (PCSK9).

~80 and 60 kDa observed (proprotein and cleaved form); 74.29 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

Western Blotting Analysis: A representative lot detected NARC-1 (PCSK9) in Western Blotting applications (Zhang, D.W., et. al. (2008). Proc Natl Acad Sci USA. 105(35):13045-50; Laggace, T.A., et. al. (2006). J Clin Invest. 116(11):2995-3005; Zhang, D.W., et. al. (2007). J Biol Chem. 282(25):18602-12).

Immunocytochemistry Analysis: A representative lot detected NARC-1 (PCSK9) in Immunocytochemistry applications (Zhang, D.W., et. al. (2007). J Biol Chem. 282(25):18602-12).

Immunoprecipitation Analysis: A representative lot immunoprecipitated NARC-1 (PCSK9) in Immunoprecipitation applications (Zhang, D.W., et. al. (2007). J Biol Chem. 282(25):18602-12).

ELISA Analysis: A representative lot detected NARC-1 (PCSK9) in ELISA applications (Laggace, T.A., et. al. (2006). J Clin Invest. 116(11):2995-3005; Lakoski, S.G., et. al. (2009). J Clin Endocrinol Metab. 94(7):2537-43).

Clone 15A6 is a mouse monoclonal antibody that specifically detects Proprotein convertase 9 (NARC-1) and its cleaved form in human cells.

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human lung tissue lysates.

Western Blotting Analysis: 4 µg/mL of this antibody detected NARC-1 (PCSK9) in human lung tissue lysates.

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