Anti-ADAMTS1 Mouse pAb (1B8)

Anti-ADAMTS1, a mouse polyclonal antibody, recognizes human ADAMTS1 protein. It is validated for ELISA, and Western blotting.

Purified mouse monoclonal antibody. Recognizes the ADAMTS1 protein.

Recognizes the ADAMTS1 protein.

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.

A recombinant polypeptide corresponding to amino acids 858-968 of human ADAMTS1, expressed as a GST fusion protein

ELISA (see comments)
Immunoblotting (1-5 g/ml)

In PBS, pH 7.27.

Following initial thaw, aliquot and freeze (-20°C).

For ELISA, this antibody can be used as the capture antibody; recommended concentration is 10 ng/ml, 1 µg/well, 100 µl total volume. Variables associated with assay conditions will dictate the proper working dilution.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Toxicity: Regulatory Review (Z)