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Merck
CN

XL-85K

Multi-Species Leptin RIA

125I (<3 μCi, <111 kBq)

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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description

ED<sub>80</sub> = 3.0 ± 0.28 ng/mL HE ED<sub>50</sub> = 8.1 ± 0.60 ng/mL HE ED<sub>20</sub> = 24.4 ± 2.0 ng/mL HE, HE = Human Equivalent , analytes available: Leptin, for protein analysis, 1-50 ng/mL (standard curve range; human equivalent)

feature

accuracy 83–104%

species reactivity

mouse, rat, human

technique(s)

radioimmunoassay: suitable

detection method

radioactive

Quality Level

General description

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Application

Two-day disequilibrium incubationat 4°C. Sample volume 100 µL serum, plasma, or tissue culture media

Biochem/physiol Actions

Human Leptin 100% Porcine Leptin 67% Rat Leptin 61% Mouse Leptin 73% Human Insulin Not Detectable Human Proinsulin Not Detectable Human C-Peptide Not Detectable Rat Insulin Not Detectable Glucagon Not Detectable IGF-I Not Detectable Canine Lepti

Analysis Note

Linearity 94–115%

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

法规信息

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"Bring your biomarkers to life by using Merck Millipore’s long-trusted assays for single protein detection. By choosing our GyroMark™ HT, ELISA or RIA kits, you’ll be building on our 25+ years experience inmetabolism, neuroscience, toxicity and cytokine research. To ensure lot-to-lot consistency, our kits are developed, manufactured and shipped under stringent quality regulations. We understand that many research projects last months, even years, and you need to know that each kit will produce the same results, lot after lot. Plus, several of our key assays match the standards of the prestigious World Health Organization (WHO)*. These kits are developed and tested to meet WHO parameters. Provided to you in smaller and more ecologically-friendly packaging, Merck Millipore’s assays will exceed your research expectations."

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