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经验公式（希尔记法）:
C10H12Li4N5O12P3S
化学文摘社编号:
分子量:
546.98
PubChem Substance ID:
UNSPSC Code:
12352204
Beilstein/REAXYS Number:
6265083
MDL number:
SMILES string
[Li+].[Li+].[Li+].[Li+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
InChI key
DWQFDOIBOYDYKH-KWIZKVQNSA-J
form
solid
mol wt
Mr 523.2 (ATP-γ-S), Mr 547.0 (ATP-γ-S-Li4)
packaging
pkg of 25 mg
manufacturer/tradename
Roche
storage condition
protect from light
General description
ATP-γ-S is a substrate and inhibitor of ATP-dependent enzyme systems. It is hydrolyzed very slowly by phosphatases and most ATPases. Once thiophosphorylated, proteins are resistant to protein phosphatases.
Preparation Note
Reconstituted aqueous solutions may lose content up to 10% year if stored at
-15 to -25 °C.
-15 to -25 °C.
Store at -15 to -25 °C. (Store dry! Repeated freezing and thawing does not harm.)
Analysis Note
Contaminants: Approximately 10% ADP (enzymatically)
Other Notes
For life science research only. Not for use in diagnostic procedures.
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Matthew L Peck et al.
RNA (New York, N.Y.), 9(10), 1180-1187 (2003-09-18)
Whereas ATPgammaS is often considered a nonhydrolyzable substrate for ATPases, we present evidence that ATPgammaS is a good substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eIF4A. In the presence of saturating single-stranded poly(U) RNA, eIF4A hydrolyzes
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