产品名称
氨苄西林, 95% (from N), solubility: (Soluble in aqueous solutions)
SMILES string
[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O
InChI
1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1
InChI key
AVKUERGKIZMTKX-NJBDSQKTSA-N
description
C16H18N3O4SNa (Formula)
assay
95% (from N)
mol wt
Mr 371.4
packaging
pkg of 5 g (10835242001)
pkg of 50 g (10835269001)
manufacturer/tradename
Roche
mp
208 °C (dec.) (lit.)
solubility
soluble (Soluble in aqueous solutions)
shipped in
wet ice
storage temp.
2-8°C
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Application
氨苄青霉素已被用于选择带有质粒的耐药菌落的基因克隆策略。仅用于生命科学研究。不用于诊断操作。
Biochem/physiol Actions
β-内酰胺可被β-内酰胺酶失活。因此，氨苄青霉素是与β-内酰胺酶抑制剂一起使用的。
作用机制：氨苄西林是一种半合成的青霉素和ß-内酰胺抗生素，其通过灭活位于细菌的细胞膜内表面的转肽酶从而抑制细菌细胞壁合成。
耐药性机制：ß-内酰胺酶切开氨苄青霉素的ß-内酰胺环,使其失去活性。
抗菌谱：对革兰氏阳性菌（类似于苄青霉素）和革兰氏阴性菌（类似于四环素和氯霉素）均有效。
耐药性机制：ß-内酰胺酶切开氨苄青霉素的ß-内酰胺环,使其失去活性。
抗菌谱：对革兰氏阳性菌（类似于苄青霉素）和革兰氏阴性菌（类似于四环素和氯霉素）均有效。
General description
6-[D(-)-α-氨基苯基乙酰胺基]-青霉烷酸
溶解度：可溶于水溶液
溶解度：可溶于水溶液
内容物：钠盐
Other Notes
仅用于生命科学研究。不可用于诊断。
法规信息
涉药品监管产品
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