01-1340
丙烯腈
SAJ special grade, ≥99.0%
别名:
乙烯基氰
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关于此项目
线性分子式:
CH2=CHCN
化学文摘社编号:
分子量:
53.06
EC Number:
203-466-5
UNSPSC Code:
12352300
PubChem Substance ID:
Beilstein/REAXYS Number:
605310
MDL number:
InChI key
NLHHRLWOUZZQLW-UHFFFAOYSA-N
InChI
1S/C3H3N/c1-2-3-4/h2H,1H2
SMILES string
C=CC#N
grade
SAJ special grade
vapor density
1.83 (vs air)
vapor pressure
86 mmHg ( 20 °C)
assay
≥99.0%
autoignition temp.
897 °F
expl. lim.
17 %
availability
available only in Japan
bp
77 °C (lit.)
mp
−83 °C (lit.)
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Application
丙烯腈可用于制造丙烯酸纤维、树脂(丙烯腈-丁二烯-苯乙烯、苯乙烯-丙烯腈等)以及丁腈橡胶(丁二烯-丙烯腈)。
Biochem/physiol Actions
属工业致癌物，对大鼠具有多位点致癌性，也可能对人体具有致癌性。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - Skin Sens. 1B - STOT SE 3
target_organs
Respiratory system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
23.0 °F - closed cup
flash_point_c
-5 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
R A Woutersen
Scandinavian journal of work, environment & health, 24 Suppl 2, 5-9 (1998-08-26)
Acrylonitrile is a monomer used extensively as a raw material in the manufacturing of acrylic fibers, plastics, synthetic rubbers, and acrylamide. It has been classified as a probable human carcinogen according to the results of numerous chronic rat bioassays. The
R Thier et al.
Archives of toxicology, 74(4-5), 184-189 (2000-08-26)
The high acute toxicity of acrylonitrile may be a result of its intrinsic biological reactivity or of its metabolite cyanide. Intravenous N-acetylcysteine has been recommended for treatment of accidental intoxications in acrylonitrile workers, but such recommendations vary internationally. Acrylonitrile is
Philip Cole et al.
Regulatory toxicology and pharmacology : RTP, 52(3), 342-351 (2008-10-18)
Several retrospective cohort epidemiology studies evaluated a number of health outcomes in workers exposed to acrylonitrile (AN). The epidemiology studies included in this review have been published since 1970 and were identified through Ovid and MEDLINE retrieval services using search
Acrylonitrile and human cancer--an overview.
D Coggon et al.
Scandinavian journal of work, environment & health, 24 Suppl 2, 81-82 (1998-08-26)
A Léonard et al.
Mutation research, 436(3), 263-283 (1999-06-04)
Acrylonitrile (AN) is an important intermediary for the synthesis of a variety of organic products, such as artificial fibres, household articles and resins. Although acute effects are the primary concern for an exposure to AN, potential genotoxic, carcinogenic and teratogenic
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