01020
氯化乙酰胆碱
purum, ≥98.0% (AT)
别名:
ACh
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关于此项目
线性分子式:
(CH3)3N+CH2CH2OCOCH3Cl-
化学文摘社编号:
分子量:
181.66
EC Number:
200-468-8
UNSPSC Code:
12352211
MDL number:
Beilstein/REAXYS Number:
3571875
Biochem/physiol Actions
氯化乙酰胆碱，20mg/kg体重注射，减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞，巨噬细胞和中性粒细胞上的胆红素受体互作接待，降低了促炎细胞活素，比如 TNF-α,IL-1β,和IL-6。
胆碱能突触中的内源性神经递质，通过增强肌膜动作电位来触发肌肉收缩反应。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Effect of acetylcholine on mortality of mice from sepsis and proinflammatory cytokine production.
Zabrodskii, P. F.
Bulletin of experimental biology and medicine, 150, 240-342 (2011)
Yingchuan B Qi et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(12), 5319-5325 (2013-03-22)
Excitatory acetylcholine motor neurons drive Caenorhabditis elegans locomotion. Coordinating the activation states of the backward-driving A and forward-driving B class motor neurons is critical for generating sinusoidal and directional locomotion. Here, we show by in vivo calcium imaging that expression
Quantal and non-quantal acetylcholine release at neuromuscular junctions of muscles of different types in a model of hypogravity.
O V Tyapkina et al.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections, 448, 4-6 (2013-03-13)
Katsura Nozawa et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(9), 3408-3413 (2009-02-13)
Serotonin (5-hydroxytryptamine; 5-HT) is abundantly present throughout the gastrointestinal tract and stored mostly in enterochromaffin (EC) cells, which are located on the mucosal surface. 5-HT released from EC cells stimulate both intrinsic and extrinsic nerves, which results in various physiological
Rosalyn J Moran et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8227-8236 (2013-05-10)
Acetylcholine (ACh) is a neuromodulatory transmitter implicated in perception and learning under uncertainty. This study combined computational simulations and pharmaco-electroencephalography in humans, to test a formulation of perceptual inference based upon the free energy principle. This formulation suggests that ACh
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