InChI key
PJQLSMYMOKWUJG-UHFFFAOYSA-N
InChI
1S/C19H18O8/c1-23-11-6-5-9(7-10(11)20)17-19(26-4)16(22)14-12(27-17)8-13(24-2)18(25-3)15(14)21/h5-8,20-21H,1-4H3
SMILES string
COc1ccc(cc1O)C2=C(OC)C(=O)c3c(O)c(OC)c(OC)cc3O2
grade
primary reference standard
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
HWI
application(s)
food and beverages
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General description
Casticin is a flavonoid, widely used as an anti-inflammatory agent. It has anti-tumor properties and is considered to be a potent immunomodulatory and cytotoxic compound.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.
Exact content by quantitative NMR can be found on the certificate.
Application
It was may be used as reference standard to compare retention time and ion peaks in plant extracts during GC/MS analysis to quantify Casticin and artemetin.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jia-Kun Shen et al.
Annals of hematology, 88(8), 743-752 (2009-01-14)
Casticin, a component from Vitex rotundifolia, widely used as an anti-inflammatory agent in Chinese traditional medicine, was reported to have anti-tumor activities. This study aims to examine the anti-leukemic activity of casticin on leukemia cells and its molecular mechanism. Cell
Pamela J Weathers et al.
Planta medica, 78(10), 1024-1026 (2012-06-08)
A number of flavonoids including casticin and artemetin from Artemisia annua have shown synergism with artemisinin against Plasmodium falciparum, but it is unclear if the flavonoids are also extracted into a tea infusion of the plant. Using a tea infusion
M Ahmed Mesaik et al.
Phytotherapy research : PTR, 23(11), 1516-1520 (2009-05-15)
Casticin (1), a flavonoid isolated from the aerial parts of Vitex agnus-castus, was found to be a potent immunomodulatory and cytotoxic compound. The activity was tested in vitro for chemiluminescence, chemotaxis, T-cell proliferation and cytotoxicity. Casticin (1) exhibited a significant
Hidetomo Kikuchi et al.
International journal of oncology, 45(2), 843-852 (2014-05-27)
We have demonstrated that an extract from the ripe fruit of Vitex angus-castus (Vitex), might be a promising anticancer candidate. In order to further provide a molecular rationale for clinical development in anticancer therapy, a detailed mechanism underlying the efficacy
相关内容
Quantitative NMR for Content Assignment of Phytochemical Reference Standards
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