01970
(-)-腺苷-5′-单磷酸 一水合物
≥99.0% (HPLC)
别名:
5′-AMP, AMP, 肌肉腺苷酸
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关于此项目
经验公式（希尔记法）:
C10H14N5O7P · H2O
化学文摘社编号:
分子量:
365.24
UNSPSC Code:
41106305
MDL number:
Beilstein/REAXYS Number:
54612
eCl@ss:
32160414
assay
≥99.0% (HPLC)
optical activity
[α]20/D −48±1°, c = 2% in 2% NaOH
mp
183-188 °C (dec.) (lit.)
storage temp.
2-8°C
SMILES string
[H]O[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O
Application
Adenosine 5′-monophosphate (5′-AMP) has many uses in nature. 5′-AMP is an activator of a class of protein kinases known as AMP-activated protein kinase (AMPK).
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
5′-AMP-activated protein kinase is inactivated by adrenergic signalling in adult cardiac myocytes.
Tsuchiya Y, Denison FC, et al.
Bioscience Reports, 1415, 23-33 (2011)
Tomohito Fujimoto et al.
Biochemical and biophysical research communications, 410(1), 45-51 (2011-06-07)
Ca(2+)/calmodulin-dependent protein kinase kinase (CaMKK) phosphorylates and activates specific downstream protein kinases including CaMKI, CaMKIV and 5'-AMP-activated protein kinase. In order to examine the variety of CaMKK-mediated signaling pathways, we searched for novel CaMKK substrate(s) using N(6)-(1-methylbutyl)-ATP and genetically engineered
Makhosazane Zungu et al.
The American journal of pathology, 178(1), 4-11 (2011-01-13)
The 5'-AMP-activated protein kinase (AMPK) functions as a metabolic fuel gauge that is activated in response to environmental stressors to restore cellular energy balance. In the heart, AMPK coordinates the activation of glucose and fatty acid metabolic pathways to ensure
Giorgia Zadra et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 16(13), 3322-3328 (2010-04-29)
Although the role of metabolic syndrome (MS) and a high fat diet in prostate cancer (PCa) risk is still a matter of intense debate, it is becoming increasingly clear that obesity can cause perturbations in metabolic pathways that contribute to
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 130621-100ML | 04061838345752 |
| 130621-25ML | 04061838345769 |
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